The average train between Ladispoli and Siena takes 6h 5m and the fastest train takes 4h 15m. The train service runs several times per day from Ladispoli to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Ladispoli and Siena. The earliest departure is at 10:51 AM in the morning, and the last departure from Ladispoli is at 11:00 PM which arrives into Siena at 7:51 AM. All services require a transfer, and take on average 6h 5m. The schedules shown below are for the next available departures.

4h 39m • 1 change

5h 22m • 1 change
Arrives next day

8h 51m • 1 change

4h 39m • 1 change

4h 16m • 1 change
Arrives next day

9h 54m • 1 change

4h 39m • 1 change

4h 16m • 1 change
Arrives next day

9h 54m • 1 change

4h 39m • 1 change

4h 16m • 1 change
Arrives next day

9h 54m • 1 change
Want to know about travelling from Ladispoli to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Ladispoli to Siena. However, there are services departing from Ladispoli station and arriving at Siena station via Grosseto. The journey, including transfers, takes approximately 6h 5m.
Ladispoli to Siena train services, operated by Trenitalia, depart from Ladispoli-Cerveteri station.
Ladispoli to Siena train services, operated by Trenitalia, arrive at Siena station.
Book your Ladispoli to Siena train tickets online with Trenitalia.
The distance between Ladispoli and Siena is 163.8 km. The road distance is 238 km.
You can take a train from Ladispoli-Cerveteri to Siena via Grosseto in around 4h 16m.