The average train between Italy and Holyhead takes 29h 41m and the fastest train takes 26h 42m. The train service runs several times per day from Italy to Holyhead. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Italy and Holyhead. The earliest departure is at 12:10 PM in the afternoon, and the last departure from Italy is at 8:05 PM which arrives into Holyhead at 9:55 PM. All services require a transfer at Milano Centrale and take an average of 29h 41m. The schedules shown below are for the next available departures.
Arrives next day




30h 44m • 4 changes
Arrives next day




27h 48m • 4 changes
Arrives next day




30h 44m • 4 changes
Arrives next day




27h 48m • 4 changes
Arrives next day




30h 44m • 4 changes
Arrives next day




27h 48m • 4 changes
Arrives next day




30h 44m • 4 changes
Arrives next day




27h 48m • 4 changes
Want to know about travelling from Italy to Holyhead? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Italy to Holyhead. However, there are services departing from Italy station and arriving at Holyhead station via Milano Centrale. The journey, including transfers, takes approximately 29h 41m.
Italy to Holyhead train services, operated by ItaloTreno, depart from Roma Termini station.
Italy to Holyhead train services, operated by ItaloTreno, arrive at Holyhead station.
Book your Italy to Holyhead train tickets online with ItaloTreno, Trenitalia and 3 other operators.
The distance between Italy and Holyhead is 1,743.2 km. The road distance is 2,359 km.
You can take a train from Roma Termini to Holyhead via Milano Centrale, Lyon Part Dieu, Lille Europe, London St Pancras Intl, and London Euston in around 19h 31m.