The average train between Italy and Holyhead takes 29h 11m and the fastest train takes 25h 47m. The train service runs several times per day from Italy to Holyhead. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Italy and Holyhead. The earliest departure is at 12:10 PM in the afternoon, and the last departure from Italy is at 8:05 PM which arrives into Holyhead at 11:53 PM. All services require a transfer at Milano Centrale and take an average of 29h 11m. The schedules shown below are for the next available departures.
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25h 47m • 4 changesArrives next day




26h 50m • 4 changesArrives next day




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26h 44m • 4 changesArrives next day




30h 49m • 4 changesArrives next day




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31h 44m • 4 changesArrives next day




28h 48m • 4 changesWant to know about travelling from Italy to Holyhead? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Italy to Holyhead. However, there are services departing from Italy station and arriving at Holyhead station via Milano Centrale. The journey, including transfers, takes approximately 29h 11m.
Italy to Holyhead train services, operated by ItaloTreno, depart from Roma Termini station.
Italy to Holyhead train services, operated by ItaloTreno, arrive at Holyhead station.
Book your Italy to Holyhead train tickets online with ItaloTreno, Trenitalia and 3 other operators.
The distance between Italy and Holyhead is 1,743.2 km. The road distance is 2,357 km.
You can take a train from Roma Termini to Holyhead via Milano Centrale, Lyon Part Dieu, Lille Europe, London St Pancras Intl, and London Euston in around 19h 29m.