The average train between Isernia and Trieste takes 10h 3m and the fastest train takes 8h 6m. The train service runs several times per day from Isernia to Trieste. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Isernia and Trieste. The earliest departure is at 6:40 AM in the morning, and the last departure from Isernia is at 8:35 PM which arrives into Trieste at 11:48 AM. All services require a transfer at Roma Termini and take an average of 10h 3m. The schedules shown below are for the next available departures.


9h 4m • 2 changes


8h 6m • 2 changes


8h 35m • 2 changes
Arrives next day


15h 13m • 2 changes


9h 4m • 2 changes


8h 6m • 2 changes


8h 35m • 2 changes
Arrives next day


15h 13m • 2 changes


9h 4m • 2 changes


8h 6m • 2 changes


8h 35m • 2 changes
Arrives next day


15h 13m • 2 changes


9h 4m • 2 changes


8h 6m • 2 changes


8h 35m • 2 changes
Arrives next day


15h 30m • 2 changes


9h 4m • 2 changes


8h 6m • 2 changes


8h 35m • 2 changes
Arrives next day


15h 13m • 2 changes
Want to know about travelling from Isernia to Trieste? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Isernia to Trieste. However, there are services departing from Isernia station and arriving at Trieste station via Roma Termini. The journey, including transfers, takes approximately 10h 3m.
Isernia to Trieste train services, operated by Trenitalia, depart from Isernia station.
Isernia to Trieste train services, operated by Trenitalia, arrive at Trieste Centrale station.
Book your Isernia to Trieste train tickets online with Trenitalia, ItaloTreno and 2 other operators.
The distance between Isernia and Trieste is 452.2 km. The road distance is 897 km.
You can take a train from Isernia to Trieste Centrale via Roma Termini and Venezia Mestre in around 9h 48m.