The average train between Iserlohn and Prague takes 12h 22m and the fastest train takes 9h 55m. The train service runs several times per day from Iserlohn to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Iserlohn and Prague. The earliest departure is at 7:20 AM in the morning, and the last departure from Iserlohn is at 5:20 PM which arrives into Prague at 11:15 AM. All services require a transfer at Dortmund Hbf and take an average of 12h 22m. The schedules shown below are for the next available departures.


9h 55m • 2 changes


9h 55m • 2 changes
Arrives next day


17h 55m • 2 changes


9h 55m • 2 changes


9h 55m • 2 changes
Arrives next day


17h 55m • 2 changes
Want to know about travelling from Iserlohn to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Iserlohn to Prague. However, there are services departing from Iserlohn station and arriving at Prague station via Berlin Hbf. The journey, including transfers, takes approximately 12h 22m.
Iserlohn to Prague train services, operated by Deutsche Bahn Regio (DB Regional), depart from Dortmund Hbf station.
Iserlohn to Prague train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Praha-Holesovice station.
Book your Iserlohn to Prague train tickets online with Deutsche Bahn Regio (DB Regional), Nederlandse Spoorwegen (NS) and Danish Railways (DSB).
The distance between Iserlohn and Prague is 493.8 km. The road distance is 864 km.
You can take a train from Iserl., Stadtbahnhof to Praha-Holesovice via Dortmund Hbf and Berlin Hbf in around 10h 1m.