The average train between Avignon and Prague takes 21h 20m and the fastest train takes 19h 40m. The train service runs several times per day from Avignon to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Avignon and Prague. The earliest departure is at 1:58 PM in the afternoon, and the last departure from Avignon is at 9:37 PM which arrives into Prague at 8:21 PM. All services require a transfer at Paris Gare de Lyon and take an average of 21h 20m. The schedules shown below are for the next available departures.
Arrives next day




19h 40m • 4 changes
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22h 24m • 4 changes
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19h 40m • 4 changes
Arrives next day




22h 24m • 4 changes
Arrives next day




19h 40m • 4 changes
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24h 24m • 4 changes
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20h 23m • 4 changes
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22h 24m • 4 changes
Want to know about travelling from Avignon to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Avignon to Prague. However, there are services departing from Avignon station and arriving at Prague station via Paris Gare De Lyon. The journey, including transfers, takes approximately 21h 20m.
Avignon to Prague train services, operated by TGV inOui, depart from Avignon Tgv station.
Avignon to Prague train services, operated by TGV inOui, arrive at Praha Hlavni Nadrazi station.
Book your Avignon to Prague train tickets online with TGV inOui, Société Nationale des Chemins de fer Français (SNCF) and 2 other operators.
The distance between Avignon and Prague is 997 km. The road distance is 1,916 km.
You can take a train from Avignon Tgv to Praha Hlavni Nadrazi via Paris Gare de Lyon, Paris Gare Du Nord, Paris Est, Stuttgart Hbf, Hauptbahnhof, München Hbf, and Muenchen Hbf in around 15h 39m.