Train Holyhead to Slough from £129 | Tickets & Timetables

Trip Overview

The average train between Holyhead and Slough takes 4h 43m and the fastest train takes 4h 38m. The train service runs several times per day from Holyhead to Slough. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 43m
Duration: 284 mi
Distance: £129
Average price: 5 times a day
Frequency

Train

best

Take the train from Holyhead to London Eustontrain Holyhead - London Euston

4h 39m

£110–184

Holyhead to Slough train times

Trains run 5 times a day between Holyhead and Slough. The earliest departure is at 4:45 AM at night, and the last departure from Holyhead is at 2:48 PM which arrives into Slough at 7:31 PM. All services require a transfer at London Euston and take an average of 4h 43m. The schedules shown below are for the next available departures.

Departing Tuesday, April 28, 2026

12:48 PM → 5:30 PM
4h 42m • 2 changes
2:48 PM → 7:31 PM
4h 43m • 2 changes

Departing Wednesday, April 29, 2026

4:45 AM → 9:33 AM
4h 48m • 2 changes
6:48 AM → 11:34 AM
4h 46m • 2 changes
8:53 AM → 1:32 PM
4h 39m • 2 changes
12:48 PM → 5:30 PM
4h 42m • 2 changes
Show more

Departing Thursday, April 30, 2026

4:45 AM → 9:33 AM
4h 48m • 2 changes
6:48 AM → 11:34 AM
4h 46m • 2 changes
8:53 AM → 1:32 PM
4h 39m • 2 changes
12:48 PM → 5:30 PM
4h 42m • 2 changes
Show more

Departing Friday, May 1, 2026

4:45 AM → 9:33 AM
4h 48m • 2 changes
6:48 AM → 11:34 AM
4h 46m • 2 changes
8:53 AM → 1:32 PM
4h 39m • 2 changes
12:48 PM → 5:30 PM
4h 42m • 2 changes
Show more

Departing Saturday, May 2, 2026

6:52 AM → 11:31 AM
4h 39m • 2 changes
7:46 AM → 12:31 PM
4h 45m • 2 changes
8:48 AM → 1:31 PM
4h 43m • 2 changes
1:53 PM → 6:31 PM
4h 38m • 2 changes
Show more

Departing Sunday, May 3, 2026

9:38 AM → 2:31 PM
4h 53m • 2 changes
11:48 AM → 4:31 PM
4h 43m • 2 changes
12:47 PM → 5:31 PM
4h 44m • 2 changes
1:48 PM → 6:31 PM
4h 43m • 2 changes

Departing Monday, May 4, 2026

4:45 AM → 9:33 AM
4h 48m • 2 changes
6:48 AM → 11:34 AM
4h 46m • 2 changes
8:53 AM → 1:32 PM
4h 39m • 2 changes
12:48 PM → 5:30 PM
4h 42m • 2 changes
Show more

Frequently asked questions

Want to know about travelling from Holyhead to Slough? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.