The average train between Holyhead and Prestwich takes 3h 27m and the fastest train takes 3h 23m. There is a train service every few hours from Holyhead to Prestwich. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Holyhead and Prestwich. The earliest departure is at 4:56 AM at night, and the last departure from Holyhead is at 8:02 PM which arrives into Prestwich at 11:28 PM. All services require a transfer at Manchester Piccadilly and take an average of 3h 27m. The schedules shown below are for the next available departures.

3h 32m • 1 change

3h 29m • 1 change

3h 28m • 1 change

3h 27m • 1 change

3h 31m • 1 change

3h 30m • 1 change

3h 28m • 1 change

3h 28m • 1 change

3h 31m • 1 change

3h 30m • 1 change

3h 28m • 1 change

3h 28m • 1 change
Want to know about travelling from Holyhead to Prestwich? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Holyhead to Prestwich. However, there are services departing from Holyhead station and arriving at Prestwich station via Manchester Piccadilly. The journey, including transfers, takes approximately 3h 27m.
Holyhead to Prestwich train services, operated by Transport for Wales, depart from Holyhead station.
Holyhead to Prestwich train services, operated by Transport for Wales, arrive at Manchester Piccadilly station.
The distance between Holyhead and Prestwich is 157.7 km. The road distance is 208 km.
Transport for Wales operates a train from Holyhead to Manchester Piccadilly hourly. Tickets cost £45–85 and the journey takes 2h 51m.