Train Enschede to Mainz from €95 | Tickets & Timetables

Trip Overview

The average train between Enschede and Mainz takes 5h 15m and the fastest train takes 4h 49m. There is a train service every few hours from Enschede to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 15m
Duration: 410 km
Distance: €95
Average price: Hourly
Frequency

Train

best

Take the train from Enschede to Münster Hauptbahnhoftrain Rb64
Take the train from Münster Hauptbahnhof to Frankfurttrain 43 / ...

5h 11m

€67–174

Enschede to Mainz train times

Trains run hourly between Enschede and Mainz. The earliest departure is at 6:26 AM in the morning, and the last departure from Enschede is at 11:33 PM which arrives into Mainz at 7:23 AM. All services require a transfer at Münster Hauptbahnhof and take an average of 5h 15m. The schedules shown below are for the next available departures.

Departing Thursday, June 18, 2026

10:33 PM → 7:44 AM
Arrives next day
9h 11m • 2 changes

Departing Friday, June 19, 2026

6:26 AM → 11:22 AM
4h 56m • 2 changes
7:33 AM → 12:22 PM
4h 49m • 2 changes
8:33 AM → 1:22 PM
4h 49m • 2 changes
9:33 AM → 2:22 PM
4h 49m • 2 changes
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Departing Saturday, June 20, 2026

6:26 AM → 11:23 AM
4h 57m • 2 changes
7:33 AM → 12:23 PM
4h 50m • 2 changes
8:33 AM → 1:23 PM
4h 50m • 2 changes
9:33 AM → 2:23 PM
4h 50m • 2 changes
Show more

Departing Sunday, June 21, 2026

8:33 AM → 1:23 PM
4h 50m • 2 changes
9:33 AM → 2:23 PM
4h 50m • 2 changes
10:33 AM → 3:23 PM
4h 50m • 2 changes
11:33 AM → 4:23 PM
4h 50m • 2 changes
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Departing Monday, June 22, 2026

6:26 AM → 11:22 AM
4h 56m • 2 changes
7:33 AM → 12:22 PM
4h 49m • 2 changes
8:33 AM → 1:22 PM
4h 49m • 2 changes
9:33 AM → 2:22 PM
4h 49m • 2 changes
Show more

Frequently asked questions

Want to know about travelling from Enschede to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.