Enschede to Italy Trains

Trip Overview

The average train between Enschede and Italy takes 21h 31m and the fastest train takes 15h 51m. The train service runs several times per day from Enschede to Italy. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

21h 31m
Duration: 1,618 km
Distance: €347
Average price: 5 times a day
Frequency

Train

best

Take the train from Enschede to Muenster(Westf)Hbftrain Re
Take the train from Münster Hauptbahnhof to Basel SBBtrain 43
Take the train from Basel SBB to Luganotrain Ec
Take the train from Lugano to Milano Centraletrain
Take the train from Milano Centrale to Roma Terminitrain

16h 46m

€232–561

Enschede to Italy train times

Trains run 5 times a day between Enschede and Italy. The earliest departure is at 12:33 AM at night, and the last departure from Enschede is at 11:33 PM which arrives into Italy at 9:05 PM. All services require a transfer at Münster Hauptbahnhof and take an average of 21h 31m. The schedules shown below are for the next available departures.

Departing Monday, October 19, 2026

9:33 AM → 9:19 AM
Arrives next day
23h 46m • 4 changes
1:33 PM → 11:00 AM
Arrives next day
21h 27m • 4 changes
3:33 PM → 4:19 PM
Arrives next day
24h 46m • 4 changes
10:33 PM → 9:05 PM
Arrives next day
22h 32m • 4 changes

Departing Tuesday, October 20, 2026

7:33 AM → 11:24 PM
15h 51m • 4 changes
9:33 AM → 9:19 AM
Arrives next day
23h 46m • 4 changes
1:33 PM → 11:00 AM
Arrives next day
21h 27m • 4 changes
3:33 PM → 4:19 PM
Arrives next day
24h 46m • 4 changes
Show more

Departing Wednesday, October 21, 2026

7:33 AM → 11:24 PM
15h 51m • 4 changes
9:33 AM → 9:19 AM
Arrives next day
23h 46m • 4 changes
1:33 PM → 11:00 AM
Arrives next day
21h 27m • 4 changes
3:33 PM → 4:19 PM
Arrives next day
24h 46m • 4 changes
Show more

Departing Thursday, October 22, 2026

7:33 AM → 11:24 PM
15h 51m • 4 changes
9:33 AM → 9:19 AM
Arrives next day
23h 46m • 4 changes
1:33 PM → 11:00 AM
Arrives next day
21h 27m • 4 changes
3:33 PM → 4:19 PM
Arrives next day
24h 46m • 4 changes
Show more

Departing Friday, October 23, 2026

7:33 AM → 11:24 PM
15h 51m • 4 changes
9:33 AM → 9:19 AM
Arrives next day
23h 46m • 4 changes
1:33 PM → 11:00 AM
Arrives next day
21h 27m • 4 changes
3:33 PM → 1:24 PM
Arrives next day
21h 51m • 4 changes

Departing Saturday, October 24, 2026

12:33 AM → 9:05 PM
20h 32m • 4 changes
7:33 AM → 11:24 PM
15h 51m • 4 changes
9:33 AM → 9:19 AM
Arrives next day
24h 46m • 4 changes
1:33 PM → 11:00 AM
Arrives next day
22h 27m • 4 changes
Show more

Frequently asked questions

Want to know about travelling from Enschede to Italy? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.