Enschede to Rome Trains

Trip Overview

The average train between Enschede and Rome takes 21h 47m and the fastest train takes 15h 51m. The train service runs several times per day from Enschede to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

21h 47m
Duration: 1,618 km
Distance: €352
Average price: 5 times a day
Frequency

Train

best

Take the train from Enschede to Muenster(Westf)Hbftrain Re
Take the train from Münster Hauptbahnhof to Basel SBBtrain 43
Take the train from Basel SBB to Luganotrain Ec
Take the train from Lugano to Milano Centraletrain
Take the train from Milano Centrale to Roma Terminitrain

16h 46m

€235–571

Enschede to Rome train times

Trains run 5 times a day between Enschede and Rome. The earliest departure is at 12:33 AM at night, and the last departure from Enschede is at 11:33 PM which arrives into Rome at 9:05 PM. All services require a transfer at Münster Hauptbahnhof and take an average of 21h 47m. The schedules shown below are for the next available departures.

Departing Friday, October 23, 2026

7:33 AM → 11:24 PM
15h 51m • 4 changes
9:33 AM → 9:19 AM
Arrives next day
23h 46m • 4 changes
1:33 PM → 11:00 AM
Arrives next day
21h 27m • 4 changes
3:33 PM → 1:24 PM
Arrives next day
21h 51m • 4 changes

Departing Saturday, October 24, 2026

12:33 AM → 9:05 PM
20h 32m • 4 changes
7:33 AM → 11:24 PM
15h 51m • 4 changes
9:33 AM → 9:19 AM
Arrives next day
24h 46m • 4 changes
1:33 PM → 11:00 AM
Arrives next day
22h 27m • 4 changes
Show more

Departing Sunday, October 25, 2026

9:33 AM → 9:19 AM
Arrives next day
23h 46m • 4 changes
1:33 PM → 11:00 AM
Arrives next day
21h 27m • 4 changes
3:33 PM → 4:19 PM
Arrives next day
24h 46m • 4 changes
10:33 PM → 9:05 PM
Arrives next day
22h 32m • 4 changes

Departing Monday, October 26, 2026

7:33 AM → 11:24 PM
15h 51m • 4 changes
9:33 AM → 9:19 AM
Arrives next day
23h 46m • 4 changes
1:33 PM → 11:00 AM
Arrives next day
21h 27m • 4 changes
3:33 PM → 4:19 PM
Arrives next day
24h 46m • 4 changes
Show more

Departing Tuesday, October 27, 2026

7:33 AM → 11:24 PM
15h 51m • 4 changes
9:33 AM → 9:19 AM
Arrives next day
23h 46m • 4 changes
1:33 PM → 11:00 AM
Arrives next day
21h 27m • 4 changes
3:33 PM → 4:19 PM
Arrives next day
24h 46m • 4 changes
Show more

Departing Wednesday, October 28, 2026

7:33 AM → 11:24 PM
15h 51m • 4 changes
9:33 AM → 9:19 AM
Arrives next day
23h 46m • 4 changes
1:33 PM → 11:00 AM
Arrives next day
21h 27m • 4 changes
3:33 PM → 4:19 PM
Arrives next day
24h 46m • 4 changes
Show more

Departing Thursday, October 29, 2026

7:33 AM → 11:24 PM
15h 51m • 4 changes

Frequently asked questions

Want to know about travelling from Enschede to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.