Rome2Rio

Enschede to Rome trains

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Trip Overview

The average train between Enschede and Rome takes 21h 36m and the fastest train takes 15h 51m. The train service runs several times per day from Enschede to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

21h 36m
Duration
1,618 km
Distance
€325
Average price
5 times a day
Frequency

Enschede to Rome train times

Trains run 5 times a day between Enschede and Rome. The earliest departure is at 7:33 AM in the morning, and the last departure from Enschede is at 11:33 PM which arrives into Rome at 9:05 PM. All services require a transfer at Münster Hauptbahnhof and take an average of 21h 36m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

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    Arrives next day

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno23h 46m • 4 changes
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    Arrives next day

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno21h 27m • 4 changes
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    Arrives next day

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno24h 46m • 4 changes
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    Arrives next day

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno22h 32m • 4 changes

Departing Friday, November 13, 2026

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    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno15h 51m • 4 changes
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    Arrives next day

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno23h 46m • 4 changes
  •  → 

    Arrives next day

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno21h 27m • 4 changes
  •  → 

    Arrives next day

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno21h 51m • 4 changes
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Departing Saturday, November 14, 2026

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    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno15h 51m • 4 changes
  •  → 

    Arrives next day

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno23h 46m • 4 changes
  •  → 

    Arrives next day

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno21h 27m • 4 changes
  •  → 

    Arrives next day

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno19h 51m • 4 changes
  • Show more

Departing Sunday, November 15, 2026

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    Arrives next day

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno23h 46m • 4 changes
  •  → 

    Arrives next day

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno21h 27m • 4 changes
  •  → 

    Arrives next day

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno24h 46m • 4 changes
  •  → 

    Arrives next day

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno22h 32m • 4 changes

Departing Monday, November 16, 2026

  •  → 

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno15h 51m • 4 changes
  •  → 

    Arrives next day

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno23h 46m • 4 changes
  •  → 

    Arrives next day

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno21h 27m • 4 changes
  •  → 

    Arrives next day

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno24h 46m • 4 changes
  • Show more

Departing Tuesday, November 17, 2026

  •  → 

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno15h 51m • 4 changes
  •  → 

    Arrives next day

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno23h 46m • 4 changes
  •  → 

    Arrives next day

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno21h 27m • 4 changes
  •  → 

    Arrives next day

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno24h 46m • 4 changes
  • Show more

Departing Wednesday, November 18, 2026

  •  → 

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Intercity (DB IC)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno15h 51m • 4 changes

Frequently asked questions

Want to know about travelling from Enschede to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Enschede to Rome.ExpandLaunch map view
  • Distance: 1,617.7 km
  • Duration: 21h 36m

What companies run services between Enschede, Netherlands and Rome, Italy?

You can take a train from Enschede to Roma Termini via Münster Hauptbahnhof, Basel SBB, Lugano, and Milano Centrale in around 16h 45m.

Operators