Rome2Rio

Durham to Chicago trains

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Trip Overview

The train between Durham and Chicago takes 35h 28m. The train runs, on average, 6 times per week from Durham to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

35h 28m
Duration
1,095 mi
Distance
$717
Average price
6 times a week
Frequency

Durham to Chicago train times

Trains run 6 times a week between Durham and Chicago. The service departs Durham at 10:17 PM at night, which arrives into Chicago at 08:45:00. All services require a transfer, and take on average 35h 28m. The schedules shown below are for the next available departures.

Departing Saturday, November 14, 2026

  •  → 

    Arrives +2 days

    AmtrakAmtrak35h 28m • 1 change

Departing Sunday, November 15, 2026

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    Arrives +2 days

    AmtrakAmtrak35h 28m • 1 change

Departing Monday, November 16, 2026

  •  → 

    Arrives +2 days

    AmtrakAmtrak35h 28m • 1 change

Departing Tuesday, November 17, 2026

  •  → 

    Arrives +2 days

    AmtrakAmtrak35h 28m • 1 change

Departing Wednesday, November 18, 2026

  •  → 

    Arrives +2 days

    AmtrakAmtrak35h 28m • 1 change

Departing Thursday, November 19, 2026

  •  → 

    Arrives +2 days

    AmtrakAmtrak35h 28m • 1 change

Frequently asked questions

Want to know about travelling from Durham to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Durham to Chicago.ExpandLaunch map view
  • Distance: 1,094.8 mi
  • Duration: 35h 28m

What companies run services between Durham, NC, USA and Chicago, IL, USA?

You can take a train from Durham Amtrak Station to Chicago Union Station via Raleigh Union Station in around 26h 7m.

Operators