There are 6 ways to get from Durham to Chicago by plane, bus (Flixbus, Greyhound), train (Amtrak), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Raleigh-Durham International Airport to Chicago Midway International Airport
best- Fly from Raleigh-Durham International Airport (RDU) to Chicago Midway International Airport (MDW)RDU - MDW
4h 45m$82–438Bus
- Take the bus from Durham to Washington Union StationFlixBus N2471 / ...
- Take the bus from Washington Union Station to Chicago Bus StationGreyhound US0164
23h 40m$107–293Train (Amtrak)
- Take the train from Durham Amtrak Station to Raleigh Union StationPiedmont / ...
- Take the train from Raleigh Union Station to Chicago Union StationFloridian
26h 16m$189–1,311Drive 765.6 mi
- Drive from Durham to Chicago765.6 mi
13h 17m$140–202Fly Raleigh-Durham International Airport to Chicago O'Hare International Airport
- Fly from Raleigh-Durham International Airport (RDU) to Chicago O'Hare International Airport (ORD)RDU - ORD
5h 17m$92–398Train to Piedmont Triad International Airport, fly to Chicago O'Hare International Airport
- Take the train from Durham Amtrak Station to Greensboro
- Fly from Piedmont Triad International Airport (GSO) to Chicago O'Hare International Airport (ORD)GSO - ORD
7h 6m$89–414
Durham to Chicago by bus
Questions & Answers
The cheapest way to get from Durham to Chicago is to bus which costs $100 - $300 and takes 23h 40m.
The fastest way to get from Durham to Chicago is to fly which takes 4h 45m and costs $80 - $440.
No, there is no direct bus from Durham to Chicago station. However, there are services departing from Durham and arriving at Chicago Bus Station via Washington Union Station. The journey, including transfers, takes approximately 23h 40m.
No, there is no direct train from Durham station to Chicago station. However, there are services departing from Durham Amtrak Station and arriving at Chicago Union Station via Raleigh Union Station. The journey, including transfers, takes approximately 26h 16m.
The distance between Durham and Chicago is 662 miles. The road distance is 770.1 miles.
The best way to get from Durham to Chicago without a car is to bus which takes 23h 40m and costs $100 - $300.
It takes approximately 4h 45m to get from Durham to Chicago, including transfers.
Durham to Chicago bus services, operated by Flixbus USA, depart from Durham station.
Durham to Chicago train services, operated by Amtrak, depart from Durham Amtrak Station.
The best way to get from Durham to Chicago is to fly which takes 4h 45m and costs $80 - $440. Alternatively, you can bus, which costs $100 - $300 and takes 23h 40m, you could also train, which costs $180 - $1,400 and takes 26h 16m.
What companies run services between Durham, NC, USA and Chicago, IL, USA?
Southwest Airlines and Delta fly from Raleigh-Durham International Airport (RDU) to Chicago Midway International Airport (MDW) 4 times a day. Alternatively, you can take a bus from Durham to Chicago Bus Station via Washington Union Station in around 23h 40m.
- Website
- aa.com
Flights from Raleigh-Durham International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 35m
- When
- Every day
- Estimated price
- $60–330
Flights from Raleigh-Durham International Airport to Chicago O'Hare International Airport via Pittsburgh
- Ave. Duration
- 5h 20m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $65–340
Flights from Piedmont Triad International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 16m
- When
- Every day
- Estimated price
- $70–390
Flights from Piedmont Triad International Airport to Chicago O'Hare International Airport via Charlotte
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $75–410
Flights from Piedmont Triad International Airport to Chicago O'Hare International Airport via New York La Guardia
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- $110–550
- Website
- southwest.com
Flights from Raleigh-Durham International Airport to Chicago Midway International Airport
- Ave. Duration
- 2h 3m
- When
- Every day
- Estimated price
- $80–430
- Website
- united.com
Flights from Raleigh-Durham International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 27m
- When
- Every day
- Estimated price
- $60–330
Flights from Piedmont Triad International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 24m
- When
- Every day
- Estimated price
- $70–390
Flights from Piedmont Triad International Airport to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 5h 1m
- When
- Every day
- Estimated price
- $85–440
- Website
- delta.com
Flights from Raleigh-Durham International Airport to Chicago Midway International Airport via Detroit
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $85–450
Flights from Piedmont Triad International Airport to Chicago O'Hare International Airport via Atlanta
- Ave. Duration
- 4h 59m
- When
- Monday, Tuesday, Friday, Saturday, and Sunday
- Estimated price
- $90–460
- Website
- flyfrontier.com
Flights from Raleigh-Durham International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 28m
- When
- Tuesday and Sunday
- Estimated price
- $60–330
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Durham Amtrak Station to Raleigh Union Station
- Ave. Duration
- 39 min
- Frequency
- 5 times a day
- Estimated price
- $9–11
- Website
- https://www.amtrak.com/home.html
Train from Raleigh Union Station to Chicago Union Station
- Ave. Duration
- 24h 37m
- Frequency
- Once daily
- Estimated price
- $180–1,300
- Website
- https://www.amtrak.com/home.html
Train from Durham Amtrak Station to Greensboro
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $11–13
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Durham to Washington Union Station
- Ave. Duration
- 5h 15m
- Frequency
- 3 times a day
- Estimated price
- $40–100
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Durham to Washington Union Station
- Ave. Duration
- 7h 15m
- Frequency
- Once daily
- Estimated price
- $40–110
- Website
- https://www.greyhound.com/
Bus from Washington Union Station to Chicago Bus Station
- Ave. Duration
- 17h 25m
- Frequency
- Twice daily
- Estimated price
- $65–190
- Website
- https://www.greyhound.com/
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More Questions & Answers
Durham to Chicago bus services, operated by Flixbus USA, arrive at Washington Union Station.
Chicago is 1h behind Durham. It is currently 11:41 AM in Durham and 10:41 AM in Chicago.
Durham to Chicago train services, operated by Amtrak, arrive at Raleigh Union Station.
Yes, the driving distance between Durham to Chicago is 770 miles. It takes approximately 13h 17m to drive from Durham to Chicago.
Book your Durham to Chicago train tickets online with Omio.
Book your Durham to Chicago bus tickets online with Omio and FlixBus.
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