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How to get fromDurham to Chicagoby bus, plane, bus (Flixbus, Greyhound), train (Amtrak), car, or train

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Durham to Chicago

Rome2Rio compared 6 ways to get from Durham to Chicago. The best route is Line 700 bus to Raleigh-Durham International Airport, fly to Chicago Midway International Airport, a distance of 997.918 km.

  1. Line 700 bus to Raleigh-Durham International Airport, fly to Chicago Midway International Airport

    best
    1. Take the bus from Pettigrew St at Parking Deck to Regional Transit Centerbus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Chicago Midway International Airport (MDW)plane plane RDU - MDW
    4h 52m
    $82–430

  2. Bus

    1. Take the bus from Durham to Washington Union Stationbus bus FlixBus N2471 / ...
    2. Take the bus from Washington Union Station to Chicago Bus Stationbus bus Greyhound US0164
    23h 20m
    $137–272

  3. Train (Amtrak)

    1. Take the train from Durham Amtrak Station to Raleigh Union Stationtrain train Piedmont / ...
    2. Take the train from Raleigh Union Station to Chicago Union Stationtrain train Floridian
    26h 7m
    $348–717

  4. Drive 764.7 mi

    1. Drive from Durham to Chicagocar car 764.7 mi
    13h 30m
    $140–202

  5. Line 700 bus to Raleigh-Durham International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Pettigrew St at Parking Deck to Regional Transit Centerbus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Chicago O'Hare International Airport (ORD)plane plane RDU - ORD
    5h 23m
    $278–500

  6. Train to Piedmont Triad International Airport, fly to Chicago O'Hare International Airport

    1. Take the train from Durham Amtrak Station to Greensborotrain train
    2. Fly from Piedmont Triad International Airport (GSO) to Chicago O'Hare International Airport (ORD)plane plane GSO - ORD
    5h 19m
    $115–460

Durham to Chicago by bus

Calendar14Weekly Buses
Duration23h 20mAverage Duration
Ticket$137Cheapest Price
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Questions & Answers

Map of how to get from Durham to Chicago.ExpandLaunch map view
  • Distance: 658.7 mi
  • Duration: 4h 52m

What companies run services between Durham, NC, USA and Chicago, IL, USA?

You can take a bus from Durham to Chicago Bus Station via Washington Union Station in around 23h 20m. Alternatively, you can take a train from Durham Amtrak Station to Chicago Union Station via Raleigh Union Station in around 26h 7m.

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