The average train between Didcot and Manchester takes 3h 24m and the fastest train takes 3h 18m. There is a train service every few hours from Didcot to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Didcot and Manchester. The earliest departure is at 6:04 AM in the morning, and the last departure from Didcot is at 8:37 PM which arrives into Manchester at 11:55 PM. All services require a transfer, and take on average 3h 24m. The schedules shown below are for the next available departures.

3h 25m • 1 change

3h 22m • 1 change

3h 23m • 1 change

3h 18m • 1 change

3h 25m • 1 change

3h 22m • 1 change

3h 23m • 1 change

3h 18m • 1 change

3h 25m • 1 change

3h 22m • 1 change

3h 23m • 1 change

3h 18m • 1 change
Want to know about travelling from Didcot to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Didcot to Manchester. However, there are services departing from Didcot station and arriving at Manchester station via Manchester Piccadilly. The journey, including transfers, takes approximately 3h 24m.
Didcot to Manchester train services, operated by Great Western Railway (GWR), depart from Oxford station.
Didcot to Manchester train services, operated by Great Western Railway (GWR), arrive at Manchester Piccadilly station.
Book your Didcot to Manchester train tickets online with Great Western Railway (GWR) and Cross Country.
The distance between Didcot and Manchester is 218.7 km. The road distance is 261 km.
Cross Country operates a train from Oxford to Manchester Piccadilly hourly. Tickets cost £75–120 and the journey takes 2h 49m.