The average train between Cholsey and Manchester takes 3h 53m and the fastest train takes 3h 35m. There is a train service every few hours from Cholsey to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Cholsey and Manchester. The earliest departure is at 5:16 AM in the morning, and the last departure from Cholsey is at 8:14 PM which arrives into Manchester at 12:13 AM. All services require a transfer, and take on average 3h 53m. The schedules shown below are for the next available departures.

4h 11m • 1 change

4h 11m • 1 change

4h 11m • 1 change

4h 11m • 1 change

4h 12m • 1 change

4h 2m • 1 change

3h 39m • 1 change

3h 45m • 1 change

4h 12m • 1 change

4h 2m • 1 change

3h 39m • 1 change

3h 45m • 1 change

4h 12m • 1 change

4h 2m • 1 change

3h 39m • 1 change

3h 45m • 1 change
Want to know about travelling from Cholsey to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Cholsey to Manchester. However, there are services departing from Cholsey station and arriving at Manchester station via Manchester Piccadilly. The journey, including transfers, takes approximately 3h 53m.
Cholsey to Manchester train services, operated by Great Western Railway (GWR), depart from Reading station.
Cholsey to Manchester train services, operated by Great Western Railway (GWR), arrive at Manchester Piccadilly station.
Book your Cholsey to Manchester train tickets online with Great Western Railway (GWR) and Cross Country.
The distance between Cholsey and Manchester is 224.2 km. The road distance is 309 km.
Cross Country operates a train from Reading to Manchester Piccadilly hourly. Tickets cost £95–140 and the journey takes 3h 14m.