The average train between Derby and Manchester takes 1h 44m and the fastest train takes 1h 31m. There is an hourly train service from Derby to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Derby and Manchester. The earliest departure is at 12:10 AM at night, and the last departure from Derby is at 11:40 PM which arrives into Manchester at 4:39 AM. All services require a transfer, and take on average 1h 44m. The schedules shown below are for the next available departures.

4h 25m • 1 change
1h 50m • 1 change
1h 35m • 1 change
1h 50m • 1 change
4h 25m • 1 change
1h 50m • 1 change
1h 35m • 1 change
1h 50m • 1 change
4h 40m • 1 change
2h 5m • 1 change
1h 50m • 1 change
1h 53m • 1 change
1h 38m • 1 change
1h 37m • 1 change
1h 44m • 1 change
1h 51m • 1 change
1h 50m • 1 change
1h 35m • 1 change
1h 50m • 1 change
1h 31m • 1 change
4h 50m • 1 change
1h 50m • 1 change
1h 35m • 1 change
1h 50m • 1 changeWant to know about travelling from Derby to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Derby to Manchester. However, there are services departing from Derby station and arriving at Manchester Piccadilly station via Sheffield station. The journey, including transfers, takes approximately 1h 44m.
Derby to Manchester train services, operated by Cross Country, depart from Derby station.
Derby to Manchester train services, operated by TransPennine Express, arrive at Manchester Piccadilly station.
Book your Derby to Manchester train tickets online with Omio.
The distance between Derby and Manchester is 80.1 km. The road distance is 93 km.
You can take a train from Derby to Manchester Piccadilly via Sheffield in around 1h 35m.