The average train between Colombes and Lyon takes 2h 33m and the fastest train takes 2h 22m. There is a train service every few hours from Colombes to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Colombes and Lyon. The earliest departure is at 6:00 AM in the morning, and the last departure from Colombes is at 8:39 PM which arrives into Lyon at 11:24 PM. All services require a transfer, and take on average 2h 33m. The schedules shown below are for the next available departures.

2h 52m • 1 change

2h 31m • 1 change

2h 38m • 1 change

2h 30m • 1 change

2h 52m • 1 change

2h 38m • 1 change

2h 30m • 1 change

2h 30m • 1 change

2h 33m • 1 change

2h 46m • 1 change

2h 26m • 1 change

2h 25m • 1 change
Want to know about travelling from Colombes to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Colombes to Lyon. However, there are services departing from Colombes station and arriving at Lyon station via Lyon Perrache. The journey, including transfers, takes approximately 2h 33m.
Colombes to Lyon train services, operated by Réseau Express Régional (RER Paris), depart from Paris Gare De Lyon station.
Colombes to Lyon train services, operated by Réseau Express Régional (RER Paris), arrive at Lyon Perrache station.
The distance between Colombes and Lyon is 403 km. The road distance is 444 km.
TGV inOui operates a train from Paris Gare De Lyon to Lyon Perrache hourly. Tickets cost €95–150 and the journey takes 2h 10m. Two other operators also service this route.