The average bus between Times Square and Vestal takes 5h 34m and the fastest bus takes 3h 53m. The bus service runs several times per day from Times Square to Vestal. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Times Square and Vestal. The earliest departure is at 5:15 AM in the morning, and the last departure from Times Square is at 8:00 PM which arrives into Vestal at 6:13 AM. All services require a transfer at Binghamton and take an average of 5h 34m. The schedules shown below are for the next available departures.

4h 44m • 1 change
Arrives next day
Arrives next day

4h 44m • 1 change
Want to know about travelling from Times Square to Vestal? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Times Square to Vestal. However, there are services departing from Times Square station and arriving at Vestal station via Binghamton. The journey, including transfers, takes approximately 5h 34m.
Times Square to Vestal bus services, operated by New York Trailways, depart from New York station.
Times Square to Vestal bus services, operated by New York Trailways, arrive at Binghamton station.
The distance between Times Square and Vestal is 227 km. The road distance is 311 km.
Trailways operates a bus from New York to Binghamton every 3 hours. Tickets cost $30–110 and the journey takes 3h 15m. New York Trailways also services this route 3 times a day.