The average bus between Buffalo and Vestal takes 5h 45m and the fastest bus takes 5h 18m. The bus service runs several times per day from Buffalo to Vestal. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Buffalo and Vestal. The earliest departure is at 12:55 AM at night, and the last departure from Buffalo is at 3:00 PM which arrives into Vestal at 8:44 PM. All services require a transfer at Binghamton and take an average of 5h 45m. The schedules shown below are for the next available departures.

5h 18m • 1 change

5h 48m • 1 change

5h 58m • 1 change

5h 48m • 1 change

5h 18m • 1 change

5h 48m • 1 change

5h 58m • 1 change

5h 48m • 1 change

5h 18m • 1 change

5h 48m • 1 change

5h 58m • 1 change

5h 48m • 1 change

5h 18m • 1 change

5h 48m • 1 change

5h 58m • 1 change

5h 48m • 1 change
Want to know about travelling from Buffalo to Vestal? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Buffalo to Vestal. However, there are services departing from Buffalo station and arriving at Vestal station via Binghamton. The journey, including transfers, takes approximately 5h 45m.
Buffalo to Vestal bus services, operated by Trailways, depart from Buffalo station.
Buffalo to Vestal bus services, operated by Trailways, arrive at Binghamton station.
The distance between Buffalo and Vestal is 248.1 km. The road distance is 395 km.
Flixbus USA operates a bus from Buffalo to Binghamton every 3 hours. Tickets cost $30–55 and the journey takes 5h 1m. Two other operators also service this route.