Rome2Rio

St. Louis to Roanoke buses

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Trip Overview

The bus between St. Louis and Roanoke takes 17h 40m. The bus runs, on average, 6 times per week from St. Louis to Roanoke. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

17h 40m
Duration
750 mi
Distance
$157
Average price
6 times a week
Frequency

St. Louis to Roanoke bus times

Buses run 6 times a week between St. Louis and Roanoke. The service departs St. Louis at 9:00 AM in the morning, which arrives into Roanoke at 03:40:00. All services require a transfer, and take on average 17h 40m. The schedules shown below are for the next available departures.

Departing Saturday, November 14, 2026

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    Arrives next day

    Greyhound USAGreyhound USA17h 40m • 1 change

Departing Sunday, November 15, 2026

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    Arrives next day

    Greyhound USAGreyhound USA17h 40m • 1 change

Departing Monday, November 16, 2026

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    Arrives next day

    Greyhound USAGreyhound USA17h 40m • 1 change

Departing Tuesday, November 17, 2026

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    Arrives next day

    Greyhound USAGreyhound USA17h 40m • 1 change

Departing Wednesday, November 18, 2026

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    Arrives next day

    Greyhound USAGreyhound USA17h 40m • 1 change

Departing Thursday, November 19, 2026

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    Arrives next day

    Greyhound USAGreyhound USA17h 40m • 1 change

Frequently asked questions

Want to know about travelling from St. Louis to Roanoke? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from St. Louis to Roanoke.ExpandLaunch map view
  • Distance: 750 mi
  • Duration: 17h 40m

What companies run services between St. Louis, MO, USA and Roanoke, VA, USA?

You can take a bus from St Louis Bus Station to Roanoke Bus Stop via Nashville Bus Station in around 16h.

Operators