Rome2Rio

How to get fromSt. Louis to Roanokeby plane, bus (Flixbus, Greyhound), train (Amtrak) or car

Find Transport to Roanoke

See all options

There are 5 ways to get from St. Louis to Roanoke by plane, bus (Flixbus, Greyhound), train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Roanoke Regional Airport-Woodrum Field

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Roanoke Regional Airport-Woodrum Field (ROA)plane plane STL - ROA
    6h 24m
    $106–608

  2. Bus

    cheapest
    1. Take the bus from St Louis Bus Station to Nashville Bus Stationbus bus FlixBus N2521
    2. Take the bus from Nashville Bus Station to Roanoke Bus Stopbus bus Greyhound US0600
    15h 30m
    $105–219

  3. Train (Amtrak)

    1. Take the train from St. Louis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Charlottesvilletrain train
    3. Take the train from Charlottesville to Roanoketrain train
    30h 3m
    $258–792

  4. Drive 673.4 mi

    1. Drive from St. Louis to Roanokecar car 673.4 mi
    11h 34m
    $123–178

  5. Fly to Greenbrier Valley Airport, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Greenbrier Valley Airport (LWB)plane plane STL - LWB
    2. Drive from Greenbrier Valley Airport (LWB) to Roanokecar car
    7h 49m
    $184–972

St. Louis to Roanoke by bus

Calendar7Weekly Buses
Duration15h 30mAverage Duration
Ticket$105Cheapest Price
See schedules

Questions & Answers

What companies run services between St. Louis, MO, USA and Roanoke, VA, USA?

Delta, American Airlines, and United Airlines fly from Lambert–St. Louis International Airport (STL) to Roanoke Regional Airport-Woodrum Field (ROA) hourly. Alternatively, you can take a bus from St Louis Bus Station to Roanoke Bus Stop via Nashville Bus Station in around 15h 30m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers

Trips from St. Louis

Trips to Roanoke

Popular routes