Rome2Rio

St. Louis to Manhattan buses

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Trip Overview

The average bus between St. Louis and Manhattan takes 24h 58m and the fastest bus takes 24h 45m. The bus service runs several times per day from St. Louis to Manhattan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

24h 58m
Duration
1,051 mi
Distance
$230
Average price
3 times a day
Frequency

St. Louis to Manhattan bus times

Buses run 3 times a day between St. Louis and Manhattan. The earliest departure is at 2:00 AM at night, and the last departure from St. Louis is at 2:05 PM which arrives into Manhattan at 3:55 PM. All services run direct with no transfers required, and take on average 24h 58m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

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    Arrives next day

    bus bus 24h 50m • Direct

Departing Wednesday, November 11, 2026

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    Arrives next day

    bus bus 25h 20m • Direct
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    Arrives next day

    bus bus 24h 45m • Direct
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    Arrives next day

    bus bus 24h 50m • Direct

Departing Thursday, November 12, 2026

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    Arrives next day

    bus bus 25h 20m • Direct
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    Arrives next day

    bus bus 24h 45m • Direct
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    Arrives next day

    bus bus 24h 50m • Direct

Departing Friday, November 13, 2026

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    Arrives next day

    bus bus 25h 20m • Direct
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    Arrives next day

    bus bus 24h 45m • Direct
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    Arrives next day

    bus bus 24h 50m • Direct

Departing Saturday, November 14, 2026

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    Arrives next day

    bus bus 25h 20m • Direct
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    Arrives next day

    bus bus 24h 45m • Direct
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    Arrives next day

    bus bus 24h 50m • Direct

Departing Sunday, November 15, 2026

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    Arrives next day

    bus bus 25h 20m • Direct
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    Arrives next day

    bus bus 24h 45m • Direct
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    Arrives next day

    bus bus 24h 50m • Direct

Departing Monday, November 16, 2026

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    Arrives next day

    bus bus 25h 20m • Direct
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    Arrives next day

    bus bus 24h 45m • Direct
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    Arrives next day

    bus bus 24h 50m • Direct

Frequently asked questions

Want to know about travelling from St. Louis to Manhattan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from St. Louis to Manhattan.ExpandLaunch map view
  • Distance: 1,050.6 mi
  • Duration: 24h 58m

What companies run services between St. Louis, MO, USA and Manhattan, NY, USA?

Greyhound USA operates a bus from St Louis Bus Station to Port Authority Bus Terminal 3 times a day. Tickets cost $190–290 and the journey takes 24h 45m.

Operators