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How to get fromSt. Louis to Manhattanby plane, bus (Greyhound), train (Amtrak), car, or train

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There are 9 ways to get from St. Louis to Manhattan by plane, bus (Greyhound), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Laguardia Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Laguardia Airport (LGA)plane plane STL - LGA
    4h 36m
    $146–446

  2. Fly to John F. Kennedy International Airport

    cheapest
    1. Fly from Lambert–St. Louis International Airport (STL) to John F. Kennedy International Airport (JFK)plane plane STL - JFK
    4h 49m
    $106–470

  3. Bus (Greyhound)

    1. Take the bus from St Louis Bus Station to Port Authority Bus Terminalbus bus Greyhound US0421
    24h 50m
    $150–300

  4. Train

    1. Take the train from St. Louis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Croton-Harmon Amtrak Stationtrain train
    3. Take the train from Croton-Harmon to 125th Street - Harlemtrain train
    26h 22m
    $390–852

  5. Drive 946.9 mi

    1. Drive from St. Louis to Manhattancar car 946.9 mi
    16h 37m
    $173–250

  6. Fly to Newark Liberty International Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Newark Liberty International Airport (EWR)plane plane STL - EWR
    4h 48m
    $392–830

  7. Fly to Philadelphia International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Philadelphia International Airport (PHL)plane plane STL - PHL
    2. Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain train
    6h 1m
    $176–1,406

  8. Fly to Long Island Mac Arthur Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Long Island Mac Arthur Airport (ISP)plane plane STL - ISP
    2. Take the train from Central Islip to New York Penn Stationtrain train
    8h 30m
    $138–684

  9. Fly to Westchester County Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Westchester County Airport (HPN)plane plane STL - HPN
    8h 10m
    $164–770

St. Louis to Manhattan by bus (Greyhound)

Calendar42Weekly Buses
Duration24h 50mAverage Duration
Ticket$150Cheapest Price
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Comparing Your Travel Options

Map of how to get from St. Louis to Manhattan.ExpandLaunch map view
  • Distance: 907.6 mi
  • Duration: 4h 36m

What companies run services between St. Louis, MO, USA and Manhattan, NY, USA?

American Airlines, Delta, and Southwest Airlines fly from Lambert–St. Louis International Airport (STL) to Laguardia Airport (LGA) every 2 hours. Alternatively, Greyhound USA operates a bus from St Louis Bus Station to Port Authority Bus Terminal every 4 hours. Tickets cost $150–300 and the journey takes 24h 50m.

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Train operators
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