The average bus between Houston and DeSoto takes 7h 50m and the fastest bus takes 5h 19m. The bus service runs several times per day from Houston to DeSoto. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Houston and DeSoto. The earliest departure is at 7:30 AM in the morning, and the last departure from Houston is at 6:00 PM which arrives into DeSoto at 6:15 AM. All services require a transfer at Downtown Dallas / Deep Ellum and take an average of 7h 50m. The schedules shown below are for the next available departures.


5h 19m • 2 changes


6h 15m • 2 changes


5h 59m • 2 changes


5h 35m • 2 changes


5h 19m • 2 changes


5h 35m • 2 changes
Arrives next day


12h 15m • 2 changes
Want to know about travelling from Houston to DeSoto? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Houston to DeSoto. However, there are services departing from Houston station and arriving at DeSoto station via Downtown Dallas / Deep Ellum. The journey, including transfers, takes approximately 7h 50m.
Houston to DeSoto bus services, operated by Flixbus USA, depart from Downtown Houston station.
Houston to DeSoto bus services, operated by Flixbus USA, arrive at Downtown Dallas / Deep Ellum station.
The distance between Houston and DeSoto is 344.9 km. The road distance is 424 km.
Flixbus USA operates a bus from Downtown Houston to Downtown Dallas / Deep Ellum every 4 hours. Tickets cost $30–55 and the journey takes 4h 25m.