The average bus between Southwark and Slough takes 2h 2m and the fastest bus takes 1h 32m. There is a bus service every few hours from Southwark to Slough. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Southwark and Slough. The earliest departure is at 2:53 AM at night, and the last departure from Southwark is at 11:00 PM which arrives into Slough at 12:32 AM. All services require a transfer, and take on average 2h 2m. The schedules shown below are for the next available departures.

1h 58m • 1 change

1h 58m • 1 change

1h 58m • 1 change

2h 13m • 1 change

4h 59m • 1 change

2h 1m • 1 change

1h 47m • 1 change

1h 54m • 1 change

4h 59m • 1 change

2h 1m • 1 change

1h 47m • 1 change

1h 54m • 1 change
Want to know about travelling from Southwark to Slough? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Southwark to Slough. However, there are services departing from Southwark station and arriving at Slough station via Victoria Station station. The journey, including transfers, takes approximately 2h 2m.
Southwark to Slough bus services, operated by National Express, depart from Southwark St /Blackfriars Road station.
Southwark to Slough bus services, operated by National Express, arrive at Wellington Street Stop H station.
Book your Southwark to Slough bus tickets online with National Express and Reading Buses.
The distance between Southwark and Slough is 34.1 km. The road distance is 37 km.
You can take a bus from Southwark St /Blackfriars Road to Wellington Street Stop H via Victoria Station in around 2h 10m.