The average bus between Bristol and Slough takes 2h 45m and the fastest bus takes 2h 25m. There is a bus service every few hours from Bristol to Slough. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Bristol and Slough. The earliest departure is at 12:55 AM at night, and the last departure from Bristol is at 7:50 PM which arrives into Slough at 10:27 PM. All services require a transfer, and take on average 2h 45m. The schedules shown below are for the next available departures.

2h 35m • 1 change

2h 35m • 1 change

2h 39m • 1 change

2h 41m • 1 change

2h 30m • 1 change

3h 1m • 1 change

2h 38m • 1 change

3h 1m • 1 change

2h 30m • 1 change

3h 1m • 1 change

2h 38m • 1 change

3h 1m • 1 change

2h 30m • 1 change

3h 1m • 1 change

2h 38m • 1 change

3h 1m • 1 change
Want to know about travelling from Bristol to Slough? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Bristol to Slough. However, there are services departing from Bristol station and arriving at Slough station via Heathrow Central Bus Station station. The journey, including transfers, takes approximately 2h 45m.
Bristol to Slough bus services, operated by National Express, depart from Bus Station.
Bristol to Slough bus services, operated by National Express, arrive at Heathrow Central Bus Station.
Book your Bristol to Slough bus tickets online with National Express and First Berkshire & The Thames Valley.
The distance between Bristol and Slough is 138.7 km. The road distance is 179 km.
National Express operates a bus from Bus Station to Heathrow Central Bus Station hourly. Tickets cost £19–50 and the journey takes 2h 5m.