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Duration 21h 20m
Distance 680 km
Average price 60€
Frequency 6/week

Trip overview

The average bus between Siena and Sicily takes 21h 20m and the fastest bus takes 17h 50m. The bus runs, on average, 6 times per week from Siena to Sicily. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

Bus, bus and ferry

  1. Siena
  2. Roma Tiburtina
  3. Palermo
15h 50m
54€ - 81€

Siena to Sicily bus times

Buses run six times a week between Siena and Palermo. The service departs Siena at 04:20 in the morning, which arrives into Palermo at 08:40. All services require a transfer at Rome Tiburtina Bus station and take an average of 21h 20m. The schedules shown below are for the next available departures.

Frequently asked questions

Want to know about travelling from Siena to Sicily? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport?, What is the quickest option?, How much do tickets usually cost? and many more.

There is widespread community transmission globally.
Some travel restrictions are being lifted in Italy. For the latest travel status, please check the official page for Italy.

Learn More.

No, there is no direct bus from Siena to Sicily. However, there are services departing from Siena and arriving at Palermo via Roma Tiburtina. The journey, including transfers, takes approximately 15h 50m.

More details

The distance between Siena and Sicily is 680 km.

Siena to Sicily bus services, operated by FlixBus, depart from Siena station.

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Siena to Sicily bus services, operated by Autoservizi Salemi Srl, arrive at Palermo station.

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There are 50+ hotels available in Sicily. Prices start at 75€ per night.

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What companies run services between Siena and Sicily?

Baltour operates a bus from SIENA - Pza Stazione FS-Fta SENA to PALERMO - PALERMO-P.Cairoli FS twice daily. Tickets cost 40€ - 60€ and the journey takes 16h 10m.
Bus operators
Baltour
Ave. Duration
16h 10m
Frequency
Twice daily
Estimated price
40€ - 60€
Phone
+39 0861 1991900
Email
info@baltour.it
Website
global.flixbus.com
Bus from SIENA - Pza Stazione FS-Fta SENA to PALERMO - PALERMO-P.Cairoli FS
Ave. Duration
16h 10m
Frequency
Twice daily
Estimated price
40€ - 60€
Website
Baltour

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