The average bus between Siena and Brussels takes 21h 16m and the fastest bus takes 20h 30m. There is at least one bus per day from Siena to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Siena and Brussels. The earliest departure is at 7:50 AM in the morning, and the last departure from Siena is at 3:05 PM which arrives into Brussels at 9:35 AM. All services require a transfer, and take on average 21h 16m. The schedules shown below are for the next available departures.
Want to know about travelling from Siena to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Siena to Brussels. However, there are services departing from Siena station and arriving at Brussels station via Milano, Autostazione Lampugnano. The journey, including transfers, takes approximately 21h 16m.
Siena to Brussels bus services, operated by FlixBus, depart from Siena station.
Siena to Brussels bus services, operated by FlixBus, arrive at Brussels-North train station.
Book your Siena to Brussels bus tickets online with FlixBus.
The distance between Siena and Brussels is 989.4 km. The road distance is 1,232 km.
You can take a bus from Siena to Brussels-North train station via Milan in around 19h 10m.