There are 11 ways to get from Siena to Brussels by bus, plane, train, car, or car train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Florence Peretola Airport, fly to Brussels Airport
best- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus
- Fly from Florence Peretola Airport (FLR) to Brussels Airport (BRU)plane FLR - BRU
5h 50mBus
cheapest- Take the bus from Siena to Milano, Autostazione Lampugnanobus N528 / ...
- Take the bus from Milano, Autostazione Lampugnano to Brussels-North train stationbus N836 / ...
19h 10m€55–141Bus, train
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus 131
- Take the train from Firenze S.M.N. to Torino Porta Susatrain Fr
- Take the train from Torino Porta Susa to Aeroport Cdg2 Tgv Roissytrain Tgv
- Take the train from Aeroport Cdg2 Tgv Roissy to Brussel-Zuid / Bruxelles-Miditrain Tgv
14h 37mDrive 1,231.8 km
- Drive from Siena to Brusselscar 1,231.8 km
12h 41m€189–273Bus, train to Bologna Guglielmo Marconi Airport, fly to Brussels Airport
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus
- Take the train from Firenze S.M.N. to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Brussels Airport (BRU)plane BLQ - BRU
6h 29mTrain, train to Pisa International Airport, fly to Brussels South Charleroi Airport, bus
- Take the train from Siena to Empolitrain
- Take the train from Empoli to Pisa Centraletrain
- Fly from Pisa International Airport (PSA) to Brussels South Charleroi Airport (CRL)plane PSA - CRL
- Take the bus from Charleroi Airport to Brussels Midi / Brussels South Westbus
7h€75–201Bus, train to Bologna Guglielmo Marconi Airport, fly to Brussels South Charleroi Airport
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus
- Take the train from Firenze S.M.N. to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Brussels South Charleroi Airport (CRL)plane BLQ - CRL
- Take the bus from Charleroi Airport to Brussels Midi / Brussels South Westbus
7h 16mBus to Florence Peretola Airport, fly to Amsterdam Airport Schiphol, train
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus
- Fly from Florence Peretola Airport (FLR) to Amsterdam Airport Schiphol (AMS)plane FLR - AMS
- Take the train from Schiphol Airport to Brussel-Zuidtrain
7h 54mBus via Lugano
- Take the bus from Siena Central Train Station to Lugano Via Giacomo and Filippo Cianibus Itabus
- Take the bus from Lugano to Brussels - Midi Train Stationbus BlaBlaCar Bus
20h 20m€62–102Train, bus
- Take the train from Siena to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Bologna Centraletrain Fr
- Take the bus from Bologna to Brussels-North Stationbus
24h 33mDrive, car train
- Drive from Siena to Villach Hbfcar
- Take the car train from Villach Hbf to Düsseldorf Hbfcartrain
- Drive from Düsseldorf Hbf to Brusselscar
14h 7m€217–1,171
Florence Peretola Airport (FLR) to Brussels Airport (BRU) flights
Questions & Answers
The cheapest way to get from Siena to Brussels is to bus via Lugano which costs €60 - €110 and takes 20h 20m.
The fastest way to get from Siena to Brussels is to train and fly and bus which takes 7h and costs €70 - €210.
No, there is no direct bus from Siena to Brussels station. However, there are services departing from Siena and arriving at Brussels-North train station via Milano, Autostazione Lampugnano. The journey, including transfers, takes approximately 19h 10m.
The distance between Siena and Brussels is 1023 km. The road distance is 1231.8 km.
The best way to get from Siena to Brussels without a car is to bus and train which takes 14h 37m and costs .
It takes approximately 5h 50m to get from Siena to Brussels, including transfers.
Siena to Brussels bus services, operated by FlixBus, depart from Siena station.
Siena to Brussels bus services, operated by FlixBus, arrive at Milano, Autostazione Lampugnano station.
Yes, the driving distance between Siena to Brussels is 1232 km. It takes approximately 12h 41m to drive from Siena to Brussels.
Book your Siena to Brussels bus tickets online with Omio and FlixBus.
What companies run services between Siena, Italy and Brussels, Belgium?
You can take a bus from Siena to Brussels-North train station via Milano, Autostazione Lampugnano in around 19h 10m.
- Website
- lufthansa.com
Flights from Florence Peretola Airport to Brussels Airport via Frankfurt
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- €75–390
Flights from Florence Peretola Airport to Brussels Airport via Munich
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- €80–290
Flights from Bologna Guglielmo Marconi Airport to Brussels Airport via Frankfurt
- Ave. Duration
- 3h 42m
- When
- Every day
- Estimated price
- €110–350
Flights from Bologna Guglielmo Marconi Airport to Brussels Airport via Munich
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- €75–210
Flights from Florence Peretola Airport to Amsterdam Airport Schiphol via Munich
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- €100–420
- Website
- ryanair.com
Flights from Pisa International Airport to Brussels South Charleroi Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €30–170
Flights from Bologna Guglielmo Marconi Airport to Brussels South Charleroi Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- €50–200
Flights from Bologna Guglielmo Marconi Airport to Brussels South Charleroi Airport via Vienna
- Ave. Duration
- 4h 10m
- When
- Friday
- Estimated price
- €50–200
- Website
- swiss.com
Flights from Florence Peretola Airport to Brussels Airport via Zurich
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- €80–270
Flights from Bologna Guglielmo Marconi Airport to Brussels Airport via Zurich
- Ave. Duration
- 3h 47m
- When
- Monday, Tuesday, Wednesday, Thursday, and Saturday
- Estimated price
- €75–210
Flights from Florence Peretola Airport to Amsterdam Airport Schiphol via Zurich
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- €100–250
- Website
- klm.com
Flights from Florence Peretola Airport to Amsterdam Airport Schiphol
- Ave. Duration
- 2h 13m
- When
- Every day
- Estimated price
- €60–360
- Website
- brusselsairlines.com
Flights from Florence Peretola Airport to Brussels Airport
- Ave. Duration
- 1h 50m
- When
- Monday, Wednesday, Thursday, and Sunday
- Estimated price
- €80–270
Flights from Bologna Guglielmo Marconi Airport to Brussels Airport
- Ave. Duration
- 1h 50m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- €75–210
- Website
- vueling.com
Flights from Florence Peretola Airport to Brussels Airport
- Ave. Duration
- 2h
- When
- Thursday and Sunday
- Estimated price
- €45–160
- Website
- airdolomiti.it
Flights from Florence Peretola Airport to Amsterdam Airport Schiphol via Munich
- Ave. Duration
- 3h 50m
- When
- Monday and Saturday
- Estimated price
- €140–420
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Torino Porta Susa
- Ave. Duration
- 2h 54m
- Frequency
- Hourly
- Estimated price
- €40–130
- Schedules at
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €15–35
- Schedules at
- trenitalia.com
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Torino Porta Susa to Aeroport Cdg2 Tgv Roissy
- Ave. Duration
- 5h 43m
- Frequency
- 3 times a week
- Estimated price
- €140–220
- Website
- https://www.sncf-connect.com/en-en
Train from Aeroport Cdg2 Tgv Roissy to Brussel-Zuid / Bruxelles-Midi
- Ave. Duration
- 1h 49m
- Frequency
- Every 2 hours
- Estimated price
- €30–90
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +44 343 218 6186
- Website
- eurostar.com
Train from Aeroport Cdg2 Tgv Roissy to Brussel-Zuid / Bruxelles-Midi
- Ave. Duration
- 1h 13m
- Frequency
- 4 times a week
- Estimated price
- €29–95
- Website
- https://www.eurostar.com/rw-en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 44m
- Frequency
- Twice daily
- Estimated price
- €9–10
- Website
- https://www.trenitalia.com/en.html
Train from Siena to Empoli
- Ave. Duration
- 1h 2m
- Frequency
- Hourly
- Estimated price
- €8
- Website
- https://www.trenitalia.com/en.html
Train from Empoli to Pisa Centrale
- Ave. Duration
- 46 min
- Frequency
- Every 30 minutes
- Estimated price
- €6–7
- Website
- https://www.trenitalia.com/en.html
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Once daily
- Estimated price
- €27–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- Once daily
- Estimated price
- €9–15
- Website
- https://www.trenitalia.com/en.html
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Schiphol Airport to Brussel-Zuid
- Ave. Duration
- 1h 39m
- Frequency
- Hourly
- Estimated price
- €29–130
- Website
- https://www.ns.nl/en
- Phone
- +49 (0) 221 800 20 820
- info@urlaubs-express.de
- Website
- urlaubs-express.de
Car train from Villach Hbf to Düsseldorf Hbf
- Ave. Duration
- 6h 39m
- Frequency
- Twice a week
- Estimated price
- €100–1,000
- Website
- https://urlaubs-express.de/?lang=en
- Car Single Bed
- €270–550
- Car Compartment
- €550–1,000
- Phone
- +39 055 849 0505
- servizioclienti@at-bus.it
- Website
- at-bus.it
Bus from Siena-Via Tozzi to Firenze Autostazione
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Website
- https://www.at-bus.it/en
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Siena to Milano, Autostazione Lampugnano
- Ave. Duration
- 5h 10m
- Frequency
- Every 4 hours
- Estimated price
- €11–27
- Website
- https://www.flixbus.co.uk
Bus from Milano, Autostazione Lampugnano to Brussels-North train station
- Ave. Duration
- 13h
- Frequency
- Once daily
- Estimated price
- €45–90
- Website
- https://www.flixbus.co.uk
- Website
- global.flixbus.com
Bus from Siena to Milano, Autostazione Lampugnano
- Ave. Duration
- 6h 50m
- Frequency
- Every 4 hours
- Schedules at
- global.flixbus.com
Bus from Milano, Autostazione Lampugnano to Brussels-North train station
- Ave. Duration
- 13h
- Frequency
- Once daily
- Schedules at
- global.flixbus.com
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Siena to Milano, Autostazione Lampugnano
- Ave. Duration
- 5h 45m
- Frequency
- Twice daily
- Estimated price
- €10–55
- Website
- https://www.itabus.it/en/home
Bus from Siena Central Train Station to Lugano Via Giacomo and Filippo Ciani
- Ave. Duration
- 8h
- Frequency
- Once daily
- Estimated price
- €22–45
- Website
- https://www.itabus.it/en/home
- info@flibco.com
- Website
- flibco.com
Bus from Charleroi Airport to Brussels Midi / Brussels South West
- Ave. Duration
- 55 min
- Frequency
- Every 30 minutes
- Estimated price
- €16–21
- Website
- https://www.flibco.com/en
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Lugano to Brussels - Midi Train Station
- Ave. Duration
- 11h 20m
- Frequency
- Once daily
- Estimated price
- €40–60
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +393293958604
- info@pistoiaviaggi.com
- Website
- pistoia-viaggi.it
Bus from Bologna to Brussels-North Station
- Ave. Duration
- 20h 57m
- Frequency
- Once a week
- Schedules at
- pistoia-viaggi.it
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