The average bus between Sicily and Pisa takes 22h 49m and the fastest bus takes 21h 20m. The bus service runs several times per day from Sicily to Pisa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Sicily and Pisa. The earliest departure is at 2:55 PM in the afternoon, and the last departure from Sicily is at 8:45 PM which arrives into Pisa at 6:05 PM. All services require a transfer at Stazione Centrale Pensilina Esterna and take an average of 22h 49m. The schedules shown below are for the next available departures.
Arrives next day


22h 55m • 2 changes
Arrives next day


21h 20m • 2 changes
Arrives next day


22h 54m • 2 changes
Arrives +2 days


28h 15m • 2 changes
Arrives next day


22h 55m • 2 changes
Arrives next day


21h 20m • 2 changes
Want to know about travelling from Sicily to Pisa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Sicily to Pisa. However, there are services departing from Sicily station and arriving at Pisa station via Florence Villa Constanza Bus Station station. The journey, including transfers, takes approximately 22h 49m.
Sicily to Pisa bus services, operated by AMAT Palermo S.p.A., depart from Palermo station.
Sicily to Pisa bus services, operated by AMAT Palermo S.p.A., arrive at Pisa station.
The distance between Sicily and Pisa is 750.4 km. The road distance is 1,356 km.
You can take a bus from Piazza Boiardo to Pisa via Stazione Centrale Pensilina Esterna, Palermo, and Florence Villa Constanza Bus Station in around 20h 45m.