The average bus between Sheffield and Slough takes 6h 6m and the fastest bus takes 5h 32m. The bus service runs several times per day from Sheffield to Slough. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Sheffield and Slough. The earliest departure is at 1:40 AM at night, and the last departure from Sheffield is at 5:55 PM which arrives into Slough at 11:35 PM. All services require a transfer at London Victoria and take an average of 6h 6m. The schedules shown below are for the next available departures.

7h 15m • 1 change

5h 48m • 1 change

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6h 55m • 1 change

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6h 10m • 1 change

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6h 55m • 1 change

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6h 10m • 1 change

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6h 55m • 1 change

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6h 8m • 1 change

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7h 15m • 1 change

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Want to know about travelling from Sheffield to Slough? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Sheffield to Slough. However, there are services departing from Sheffield station and arriving at Slough station via London Victoria. The journey, including transfers, takes approximately 6h 6m.
Sheffield to Slough bus services, operated by FlixBus, depart from Sheffield Interchange - City Centre station.
Sheffield to Slough bus services, operated by FlixBus, arrive at Wellington Street Stop H station.
Book your Sheffield to Slough bus tickets online with FlixBus and Reading Buses.
The distance between Sheffield and Slough is 216.5 km. The road distance is 294 km.
You can take a bus from Sheffield Interchange - City Centre to Wellington Street Stop H via London Victoria and Green Line Coach Station in around 5h 53m.