The average bus between Senec and Prague takes 5h 50m and the fastest bus takes 5h 8m. The bus service runs several times per day from Senec to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Senec and Prague. The earliest departure is at 6:27 AM in the morning, and the last departure from Senec is at 11:40 PM which arrives into Prague at 10:40 AM. All services require a transfer, and take on average 5h 50m. The schedules shown below are for the next available departures.

5h 48m • 1 change

5h 8m • 1 change

5h 53m • 1 change
Arrives next day

5h 28m • 1 change

5h 30m • 1 change

5h 38m • 1 change

5h 38m • 1 change

5h 48m • 1 change

5h 30m • 1 change

5h 38m • 1 change

5h 38m • 1 change

5h 48m • 1 change

5h 30m • 1 change

5h 38m • 1 change

5h 38m • 1 change

5h 48m • 1 change

5h 53m • 1 change

5h 38m • 1 change

5h 38m • 1 change

5h 48m • 1 change

5h 53m • 1 change

5h 38m • 1 change

5h 38m • 1 change

5h 48m • 1 change
Want to know about travelling from Senec to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Senec to Prague. However, there are services departing from Senec station and arriving at Prague station via Prague. The journey, including transfers, takes approximately 5h 50m.
Senec to Prague bus services, operated by Arriva Slovensko, depart from Bratislava, Autobusová stanica Mlynské Nivy station.
Senec to Prague bus services, operated by Arriva Slovensko, arrive at Prague station.
The distance between Senec and Prague is 300.2 km. The road distance is 364 km.
FlixBus operates a bus from Bratislava, Autobusová stanica Mlynské Nivy to Prague every 3 hours. Tickets cost Kč 550–950 and the journey takes 4h 25m.