The bus between Rochester and Des Moines takes 22h 40m. There is at least one bus per day from Rochester to Des Moines. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Rochester and Des Moines. The earliest departure is at 9:15 PM at night, and the last departure from Rochester is at 9:15 PM which arrives into Des Moines at 6:55 PM. All services require a transfer at Cleveland Bus Station and take an average of 22h 40m. The schedules shown below are for the next available departures.
Want to know about travelling from Rochester to Des Moines? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Rochester to Des Moines. However, there are services departing from Rochester station and arriving at Des Moines station via Cleveland Bus Station station. The journey, including transfers, takes approximately 22h 40m.
Rochester to Des Moines bus services, operated by Greyhound USA, depart from Rochester Bus Stop station.
Rochester to Des Moines bus services, operated by Greyhound USA, arrive at Des Moines station.
Book your Rochester to Des Moines bus tickets online with Greyhound USA.
The distance between Rochester and Des Moines is 1,323 km. The road distance is 1,531 km.
You can take a bus from Rochester Bus Stop to Des Moines via Cleveland Bus Station and Chicago Bus Station in around 21h 15m.