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How to get fromRochester to Des Moinesby plane, train, bus, bus (Flixbus, Greyhound) or car

Find Transport to Des Moines

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There are 5 ways to get from Rochester to Des Moines by plane, train, bus, bus (Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Rochester

    best
    1. Fly from Rochester (ROC) to Des Moines (DSM)plane plane ROC - DSM
    4h 54m
    $244–1,241
  2. Train, bus

    cheapest
    1. Take the train from Rochester to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123 / ...
    19h 26m
    $110–301
  3. Bus

    1. Take the bus from Rochester Bus Stop to Buffalobus bus
    2. Take the bus from Buffalo to Cleveland Bus Stationbus bus
    3. Take the bus from Cleveland Bus Station to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Bus Station to Des Moinesbus bus
    21h 59m
    $111–248
  4. Drive 915.2 mi

    1. Drive from Rochester to Des Moinescar car 915.2 mi
    15h 25m
    $167–242
  5. Bus to Buffalo Niagara International Airport, fly

    1. Take the bus from Rochester Bus Stop to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Des Moines (DSM)plane plane BUF - DSM
    6h 53m
    $283–1,442

Rochester to Des Moines by train, foot, and bus

Calendar14Weekly Services
Duration19h 26mAverage Duration
Ticket$110Cheapest Price
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Questions & Answers

What companies run services between Rochester, NY, USA and Des Moines, IA, USA?

Delta, American Airlines, and two other airlines fly from Rochester (ROC) to Des Moines (DSM) every 3 hours. Alternatively, you can take a bus from Rochester Bus Stop to Des Moines via Buffalo, Cleveland Bus Station, and Chicago Bus Station in around 21h 59m.

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