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How to get fromRoanoke to Buffaloby plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, train or bus (Greyhound)

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There are 8 ways to get from Roanoke to Buffalo by plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Roanoke Regional Airport-Woodrum Field to Buffalo Niagara International Airport

    best
    1. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Buffalo Niagara International Airport (BUF)plane plane ROA - BUF
    6h 28m
    $159–982

  2. Drive 489.7 mi

    cheapest
    1. Drive from Roanoke to Buffalocar car 489.7 mi
    9h 55m
    $90–130

  3. Bus via Newark

    1. Take the bus from Roanoke Bus Stop to Washington Union Stationbus bus
    2. Take the bus from Washington Union Station to Newark Penn Stationbus bus
    3. Take the bus from Newark Penn Station to Buffalobus bus
    19h 23m
    $109–256

  4. Train (Amtrak)

    1. Take the train from Roanoke to Ny Moynihan Train Hall At Penn Stationtrain train Northeast Regional
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train Empire Service / ...
    19h 41m
    $157–639

  5. Fly Roanoke Regional Airport-Woodrum Field to Rochester, bus

    1. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Rochester (ROC)plane plane ROA - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    7h 35m
    $115–598

  6. Train to Lynchburg Regional Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Roanoke to Lynchburgtrain train
    2. Fly from Lynchburg Regional Airport (LYH) to Buffalo Niagara International Airport (BUF)plane plane LYH - BUF
    8h 54m
    $154–1,186

  7. Train to Ronald Reagan Washington National Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Roanoke to Alexandriatrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Buffalo Niagara International Airport (BUF)plane plane DCA - BUF
    8h 34m
    $266–1,921

  8. Bus

    1. Take the bus from Salem VDOT Park & Ride to Washington Union Stationbus bus
    2. Take the bus from Washington Union Station to Harrisburg Bus Stationbus bus
    3. Take the bus from Harrisburg, Pa to Dubois, Pabus bus 731
    4. Take the bus from DuBois to Buffalobus bus
    22h
    $112–289

Roanoke to Buffalo by bus

Calendar7Weekly Buses
Duration19h 23mAverage Duration
Ticket$109Cheapest Price
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Questions & Answers

What companies run services between Roanoke, VA, USA and Buffalo, NY, USA?

United Airlines, American Airlines, and Delta fly from Roanoke Regional Airport-Woodrum Field (ROA) to Buffalo Niagara International Airport (BUF) hourly. Alternatively, you can take a bus from Roanoke Bus Stop to Buffalo via Washington Union Station and Newark Penn Station in around 19h 23m.

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