The average bus between Prescot and Southampton takes 9h 54m and the fastest bus takes 8h 20m. The bus service runs several times per day from Prescot to Southampton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Prescot and Southampton. The earliest departure is at 4:20 AM at night, and the last departure from Prescot is at 11:29 PM which arrives into Southampton at 12:40 PM. All services require a transfer at Liverpool, Liverpool One and take an average of 9h 54m. The schedules shown below are for the next available departures.



8h 20m • 3 changes



9h 59m • 3 changes



9h 53m • 3 changes
Arrives next day



13h 14m • 3 changes



8h 50m • 3 changes



9h 53m • 3 changes
Arrives next day



13h 14m • 3 changes
Want to know about travelling from Prescot to Southampton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Prescot to Southampton. However, there are services departing from Prescot station and arriving at Southampton station via Manchester Airport The Station station. The journey, including transfers, takes approximately 9h 54m.
Prescot to Southampton bus services, operated by Arriva UK, depart from Liverpool, Liverpool One station.
Prescot to Southampton bus services, operated by Arriva UK, arrive at Coach Station.
The distance between Prescot and Southampton is 296.5 km. The road distance is 414 km.
You can take a bus from Houghton Street to Coach Station via Liverpool, Liverpool One, Manchester Airport The Station, and Birmingham Coach Station in around 9h 32m.