There are 8 ways to get from Prescot to Southampton by train, bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via London
best- Take the train from Liverpool Lime Street to London Eustontrain Liverpool Lime Street - London Euston
- Take the train from London Waterloo to Southampton Centraltrain London Waterloo - Weymouth / ...
5h 1m£99–182Bus
cheapest- Take the bus from Liverpool, Liverpool One to Heathrow Terminal 5bus 802
- Take the bus from Heathrow Terminal 5 to Coach Stationbus 032 / ...
8h 50m£44–71Drive 220.2 mi
- Drive from Prescot to Southamptoncar 220.2 mi
4h 5m£55–79Train to Manchester Airport, fly to Southampton Airport
- Take the train from Rainhill to Manchester Airporttrain
- Fly from Manchester Airport (MAN) to Southampton Airport (SOU)plane MAN - SOU
3h 53m£84–208Train
- Take the train from Runcorn to Wolverhamptontrain Liverpool Lime Street - Birmingham New Street / ...
- Take the train from Wolverhampton to Southampton Centraltrain Manchester Piccadilly - Bournemouth / ...
6h 18m£90–163Train via Newport
- Take the train from Chester to Newport (S Wales)train Holyhead - Cardiff Central / ...
- Take the train from Newport (S Wales) to Southampton Centraltrain Cardiff Central - Portsmouth Harbour / ...
8h 34m£96–175Fly Liverpool to Southampton Airport
- Fly from Liverpool (LPL) to Southampton Airport (SOU)plane LPL - SOU
5h 36m£91–213Train to Manchester Airport, fly to London Heathrow Airport, bus
- Take the train from Rainhill to Manchester Airporttrain
- Fly from Manchester Airport (MAN) to London Heathrow Airport (LHR)plane MAN - LHR
- Take the bus from Heathrow Central Bus Station to Coach Stationbus
6h 1m£78–271
Prescot to Southampton by bus and train
Comparing Your Travel Options
The cheapest way to get from Prescot to Southampton is to bus which costs £40 - £75 and takes 8h 50m.
The fastest way to get from Prescot to Southampton is to train and fly which takes 3h 53m and costs £80 - £210.
No, there is no direct bus from Prescot to Southampton station. However, there are services departing from Houghton Street and arriving at Coach Station via Liverpool, Liverpool One and Heathrow Terminal 5. The journey, including transfers, takes approximately 8h 50m.
No, there is no direct train from Prescot to Southampton. However, there are services departing from Prescot and arriving at Southampton Central via Liverpool Lime Street, Euston station and London Waterloo. The journey, including transfers, takes approximately 5h 1m.
The distance between Prescot and Southampton is 283 miles. The road distance is 221.5 miles.
The best way to get from Prescot to Southampton without a car is to train via London which takes 5h 1m and costs £95 - £190.
It takes approximately 5h 1m to get from Prescot to Southampton, including transfers.
Prescot to Southampton bus services, operated by National Express, depart from Liverpool, Liverpool One station.
Prescot to Southampton train services, operated by Avanti West Coast, depart from Liverpool Lime Street station.
The best way to get from Prescot to Southampton is to train via London which takes 5h 1m and costs £95 - £190. Alternatively, you can bus, which costs £40 - £75 and takes 8h 50m, you could also fly, which costs £90 - £220 and takes 5h 36m.
What companies run services between Prescot, England and Southampton, England?
You can take a train from Prescot to Southampton Central via Liverpool Lime Street, London Euston, Euston station, Waterloo Station, and London Waterloo in around 5h 1m. Alternatively, you can take a bus from Houghton Street to Coach Station via Liverpool, Liverpool One and Heathrow Terminal 5 in around 8h 50m.
- Website
- britishairways.com
Flights from Manchester Airport to Southampton Airport
- Ave. Duration
- 50 min
- When
- Every day
- Estimated price
- £75–160
Flights from Liverpool to Southampton Airport via Dublin
- Ave. Duration
- 3h 43m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- £95–200
Flights from Liverpool to Southampton Airport via Belfast City
- Ave. Duration
- 4h 45m
- When
- Monday, Wednesday, Thursday, and Saturday
- Estimated price
- £95–200
Flights from Manchester Airport to London Heathrow Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- £50–210
- Phone
- +44 (0)345 528 0253
- Website
- Avanti West Coast
Train from Liverpool Lime Street to London Euston
- Ave. Duration
- 2h 20m
- Frequency
- Hourly
- Estimated price
- £65–110
- Website
- Avanti West Coast
Train from Runcorn to Wolverhampton
- Ave. Duration
- 53 min
- Frequency
- Once a week
- Estimated price
- £21–35
- Website
- Avanti West Coast
- Phone
- +44 (0)3717 81 81 81
- Website
- National Express
Bus from Liverpool, Liverpool One to Heathrow Terminal 5
- Ave. Duration
- 4h 50m
- Frequency
- Once daily
- Estimated price
- £35–55
- Website
- National Express
Bus from Heathrow Terminal 5 to Coach Station
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- £9–16
- Website
- National Express
Bus from Heathrow Central Bus Station to Coach Station
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- £10–17
- Website
- National Express
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Booking & Getting There
Prescot to Southampton bus services, operated by National Express, arrive at Heathrow Terminal 5 station.
Prescot to Southampton train services, operated by Avanti West Coast, arrive at London Euston station.
Yes, the driving distance between Prescot to Southampton is 221 miles. It takes approximately 4h 5m to drive from Prescot to Southampton.
Book your Prescot to Southampton train tickets online with Omio.
There are 1974+ hotels available in Southampton.









