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How to get fromPrescot to Southamptonby train, bus, car or plane

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There are 6 ways to get from Prescot to Southampton by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Runcorn to Wolverhamptontrain train Liverpool Lime Street - Birmingham New Street / ...
    2. Take the train from Wolverhampton to Southampton Centraltrain train Manchester Piccadilly - Bournemouth / ...
    6h 5m
    £104–178
  2. Bus

    cheapest
    1. Take the bus from Liverpool, Liverpool One to Birmingham Coach Stationbus bus 550 / ...
    2. Take the bus from Birmingham Coach Station to Coach Stationbus bus 160
    9h 18m
    £45–108
  3. Drive 220.7 mi

    1. Drive from Prescot to Southamptoncar car 220.7 mi
    4h 3m
    £54–78
  4. Train to Manchester Airport, fly

    1. Take the train from Rainhill to Manchester Airporttrain train
    2. Fly from Manchester Airport (MAN) to Southampton Airport (SOU)plane plane MAN - SOU
    4h 4m
    £80–172
  5. Train via Newport

    1. Take the train from Chester to Newport (S Wales)train train Holyhead - Cardiff Central / ...
    2. Take the train from Newport (S Wales) to Southampton Centraltrain train Cardiff Central - Portsmouth Harbour / ...
    8h 36m
    £107–201
  6. Fly from Liverpool

    1. Fly from Liverpool (LPL) to Southampton Airport (SOU)plane plane LPL - SOU
    5h 42m
    £78–208

Prescot to Southampton by bus and train

Calendar101Weekly Services
Duration6h 5mAverage Duration
Ticket£104Cheapest Price
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Questions & Answers

What companies run services between Prescot, England and Southampton, England?

You can take a bus from Queens Road to Southampton Central via Station Road, Runcorn, and Wolverhampton in around 6h 5m. Alternatively, you can take a bus from Houghton Street to Coach Station via Liverpool, Liverpool One and Birmingham Coach Station in around 9h 18m.

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