The average bus between Pittsburgh and Hyannis takes 17h 58m and the fastest bus takes 15h 45m. The bus service runs several times per day from Pittsburgh to Hyannis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Pittsburgh and Hyannis. The earliest departure is at 1:00 PM in the afternoon, and the last departure from Pittsburgh is at 9:45 PM which arrives into Hyannis at 1:30 PM. All services require a transfer at New York Midtown and take an average of 17h 58m. The schedules shown below are for the next available departures.
Arrives next day


20h 35m • 2 changes
Arrives next day


15h 45m • 2 changes
Arrives next day


20h 35m • 2 changes
Arrives next day


15h 45m • 2 changes
Arrives next day


20h 35m • 2 changes
Arrives next day


15h 45m • 2 changes
Arrives next day


20h 35m • 2 changes
Arrives next day


15h 45m • 2 changes
Want to know about travelling from Pittsburgh to Hyannis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Pittsburgh to Hyannis. However, there are services departing from Pittsburgh station and arriving at Hyannis station via New York Midtown. The journey, including transfers, takes approximately 17h 58m.
Pittsburgh to Hyannis bus services, operated by Flixbus USA, depart from Pittsburgh Intermodal Station.
Pittsburgh to Hyannis bus services, operated by Flixbus USA, arrive at Hyannis Transportation Center station.
Book your Pittsburgh to Hyannis bus tickets online with Flixbus USA and Peter Pan Bus Lines.
The distance between Pittsburgh and Hyannis is 825.2 km. The road distance is 1,178 km.
You can take a bus from Pittsburgh Intermodal Station to Hyannis Transportation Center via New York Midtown, Boston, and Boston South Station in around 16h 38m.