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Keene to Hyannis buses

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Trip Overview

The bus between Keene and Hyannis takes 7h 50m. There is at least one bus per day from Keene to Hyannis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

7h 50m
Duration
240 mi
Distance
$65
Average price
Once daily
Frequency

Keene to Hyannis bus times

Buses run once daily between Keene and Hyannis. The service departs Keene at 7:25 AM in the morning, which arrives into Hyannis at 15:15:00. All services require a transfer at Springfield Union Station and take an average of 7h 50m. The schedules shown below are for the next available departures.

Departing Sunday, November 15, 2026

  •  → 

    Greyhound USAFlixbus USAPlymouth & Brockton7h 50m • 2 changes

Departing Monday, November 16, 2026

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    Greyhound USAFlixbus USAPlymouth & Brockton7h 50m • 2 changes

Departing Tuesday, November 17, 2026

  •  → 

    Greyhound USAGreyhound USAPlymouth & Brockton7h 50m • 2 changes

Departing Wednesday, November 18, 2026

  •  → 

    Greyhound USAFlixbus USAPlymouth & Brockton7h 50m • 2 changes

Departing Thursday, November 19, 2026

  •  → 

    Greyhound USAFlixbus USAPlymouth & Brockton7h 50m • 2 changes

Departing Friday, November 20, 2026

  •  → 

    Greyhound USAFlixbus USAPlymouth & Brockton7h 50m • 2 changes

Frequently asked questions

Want to know about travelling from Keene to Hyannis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Keene to Hyannis.ExpandLaunch map view
  • Distance: 240 mi
  • Duration: 7h 50m

What companies run services between Keene, NH, USA and Hyannis, MA, USA?

You can take a bus from Keene to Hyannis Transportation Center via Springfield Union Station, Boston, and Boston South Buses in around 7h 55m.

Operators