Rome2Rio

Pittsburgh to Chicago Loop buses

Find Transport to Chicago Loop

View schedule
QR code to download the Rome2Rio app

Download the Rome2Rio travel app

Scan QR code with your phone to download the app

Download on the App StoreGet it on Google Play

Trip Overview

The average bus between Pittsburgh and Chicago Loop takes 11h 47m and the fastest bus takes 10h 17m. The bus service runs several times per day from Pittsburgh to Chicago Loop. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

11h 47m
Duration
479 mi
Distance
$104
Average price
3 times a day
Frequency

Pittsburgh to Chicago Loop bus times

Buses run 3 times a day between Pittsburgh and Chicago Loop. The earliest departure is at 12:55 AM at night, and the last departure from Pittsburgh is at 7:45 PM which arrives into Chicago Loop at 6:41 AM. All services require a transfer at Chicago Bus Station and take an average of 11h 47m. The schedules shown below are for the next available departures.

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    Flixbus USAChicago Transit (CTA)11h 56m • 1 change

Departing Sunday, November 15, 2026

  •  → 

    Greyhound USAChicago Transit (CTA)10h 17m • 1 change
  •  → 

    Flixbus USAChicago Transit (CTA)13h 8m • 1 change
  •  → 

    Greyhound USAChicago Transit (CTA)12h 49m • 1 change
  •  → 

    Arrives next day

    Flixbus USAChicago Transit (CTA)11h 41m • 1 change

Departing Monday, November 16, 2026

  •  → 

    Greyhound USAChicago Transit (CTA)10h 19m • 1 change
  •  → 

    Flixbus USAChicago Transit (CTA)13h 7m • 1 change
  •  → 

    Greyhound USAChicago Transit (CTA)12h 45m • 1 change
  •  → 

    Arrives next day

    Flixbus USAChicago Transit (CTA)11h 41m • 1 change

Departing Tuesday, November 17, 2026

  •  → 

    Greyhound USAChicago Transit (CTA)10h 19m • 1 change
  •  → 

    Greyhound USAChicago Transit (CTA)12h 45m • 1 change

Departing Wednesday, November 18, 2026

  •  → 

    Greyhound USAChicago Transit (CTA)10h 19m • 1 change
  •  → 

    Greyhound USAChicago Transit (CTA)12h 45m • 1 change
  •  → 

    Arrives next day

    Flixbus USAChicago Transit (CTA)11h 41m • 1 change

Departing Thursday, November 19, 2026

  •  → 

    Greyhound USAChicago Transit (CTA)10h 19m • 1 change
  •  → 

    Greyhound USAChicago Transit (CTA)12h 45m • 1 change
  •  → 

    Arrives next day

    Flixbus USAChicago Transit (CTA)11h 41m • 1 change

Departing Friday, November 20, 2026

  •  → 

    Greyhound USAChicago Transit (CTA)10h 19m • 1 change
  •  → 

    Greyhound USAChicago Transit (CTA)12h 45m • 1 change

Frequently asked questions

Want to know about travelling from Pittsburgh to Chicago Loop? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Pittsburgh to Chicago Loop.ExpandLaunch map view
  • Distance: 479 mi
  • Duration: 11h 47m

What companies run services between Pittsburgh, PA, USA and Chicago Loop, IL, USA?

Greyhound USA operates a bus from Pittsburgh Intermodal Station to Chicago Bus Station twice daily. Tickets cost $85–130 and the journey takes 10h 5m. Flixbus USA also services this route once daily.

Operators