There are 8 ways to get from Pittsburgh to Chicago Loop by bus, plane, train (Amtrak), bus (Greyhound, Flixbus), car, train, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Pittsburgh International Airport, fly to Chicago Midway International Airport
best- Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus
- Fly from Pittsburgh International Airport (PIT) to Chicago Midway International Airport (MDW)plane PIT - MDW
4h 33mTrain (Amtrak)
cheapest- Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain Floridian
9h 46m$60–190Bus
- Take the bus from Pittsburgh Intermodal Station to Chicago Bus Stationbus Greyhound US0164
10h 34m$61–159Drive 460.8 mi
- Drive from Pittsburgh to Chicago Loopcar 460.8 mi
7h 36m$85–122Bus to Pittsburgh International Airport, fly to Chicago O'Hare International Airport
- Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus
- Fly from Pittsburgh International Airport (PIT) to Chicago O'Hare International Airport (ORD)plane PIT - ORD
4h 50mTrain to Johnstown-Cambria County Airport, fly to Chicago O'Hare International Airport
- Take the train from Pittsburgh Amtrak Station to Johnstown Amtrak Stationtrain
- Fly from Johnstown-Cambria County Airport (JST) to Chicago O'Hare International Airport (ORD)plane JST - ORD
5h 37m$80–324Train to Cleveland-Hopkins International Airport, fly to Chicago Midway International Airport
- Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain
- Fly from Cleveland-Hopkins International Airport (CLE) to Chicago Midway International Airport (MDW)plane CLE - MDW
7h 2m$97–523Bus via Chicago (Flixbus)
- Take the bus from Pittsburgh Intermodal Station to Chicagobus FlixBus N2640
11h 25m$64–107
Pittsburgh to Chicago Loop by train (Amtrak)
Questions & Answers
The cheapest way to get from Pittsburgh to Chicago Loop is to bus which costs $60 - $160 and takes 10h 34m.
The fastest way to get from Pittsburgh to Chicago Loop is to train and fly which takes 5h 37m and costs $75 - $330.
No, there is no direct bus from Pittsburgh station to Chicago Loop. However, there are services departing from Pittsburgh Intermodal Station and arriving at Washington & Lasalle via Jefferson & Harrison. The journey, including transfers, takes approximately 10h 34m.
Yes, there is a direct train departing from Pittsburgh Amtrak Station station and arriving at Chicago Union Station station. Services depart once daily, and operate every day. The journey takes approximately 9h 46m.
The distance between Pittsburgh and Chicago Loop is 439 miles. The road distance is 463.5 miles.
The best way to get from Pittsburgh to Chicago Loop without a car is to train which takes 9h 46m and costs $60 - $190.
It takes approximately 4h 33m to get from Pittsburgh to Chicago Loop, including transfers.
Pittsburgh to Chicago Loop bus services, operated by Greyhound USA, depart from Pittsburgh Intermodal Station.
Pittsburgh to Chicago Loop train services, operated by Amtrak, depart from Pittsburgh Amtrak Station.
The best way to get from Pittsburgh to Chicago Loop is to train which takes 9h 46m and costs $60 - $190. Alternatively, you can bus, which costs $60 - $160 and takes 10h 34m.
What companies run services between Pittsburgh, PA, USA and Chicago Loop, IL, USA?
Amtrak operates a train from Pittsburgh Amtrak Station to Chicago Union Station once daily. Tickets cost $60–190 and the journey takes 9h 46m. Alternatively, Greyhound USA operates a bus from Pittsburgh Intermodal Station to Chicago Bus Station twice daily. Tickets cost $55–160 and the journey takes 10h 20m. Flixbus USA also services this route once daily.
- Website
- southwest.com
Flights from Pittsburgh International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $65–420
Flights from Cleveland-Hopkins International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $65–440
- Website
- united.com
Flights from Pittsburgh International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 53m
- When
- Every day
- Estimated price
- $45–300
Flights from Pittsburgh International Airport to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 4h 29m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $65–360
Flights from Johnstown-Cambria County Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 11m
- When
- Every day
- Estimated price
- $45–280
- Website
- aa.com
Flights from Pittsburgh International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 3m
- When
- Every day
- Estimated price
- $45–300
- Website
- delta.com
Flights from Pittsburgh International Airport to Chicago O'Hare International Airport via Detroit
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $50–300
Flights from Cleveland-Hopkins International Airport to Chicago Midway International Airport via Detroit
- Ave. Duration
- 3h 23m
- When
- Every day
- Estimated price
- $65–440
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Pittsburgh Amtrak Station to Chicago Union Station
- Ave. Duration
- 9h 46m
- Frequency
- Once daily
- Estimated price
- $60–190
- Website
- https://www.amtrak.com/home.html
Train from Pittsburgh Amtrak Station to Johnstown Amtrak Station
- Ave. Duration
- 1h 32m
- Frequency
- Once daily
- Estimated price
- $18–22
- Website
- https://www.amtrak.com/home.html
Train from Pittsburgh Amtrak Station to Cleveland Amtrak
- Ave. Duration
- 2h 54m
- Frequency
- Once daily
- Estimated price
- $27–75
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 412-442-2000
- Website
- rideprt.org
Bus from Seventh Ave + Smithfield St to Pittsburgh International Airport
- Ave. Duration
- 49 min
- Frequency
- Hourly
- Website
- https://www.rideprt.org
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Pittsburgh Intermodal Station to Chicago Bus Station
- Ave. Duration
- 10h 20m
- Frequency
- Twice daily
- Estimated price
- $55–160
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Pittsburgh Intermodal Station to Chicago Bus Station
- Ave. Duration
- 11h 25m
- Frequency
- Once daily
- Estimated price
- $60–120
- Schedules at
- flixbus.com
Bus from Pittsburgh Intermodal Station to Chicago
- Ave. Duration
- 10h 55m
- Frequency
- Once daily
- Estimated price
- $60–110
- Schedules at
- flixbus.com
- Adult
- $60–110
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
Pittsburgh to Chicago Loop bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Chicago Loop is 1h behind Pittsburgh. It is currently 12:43 AM in Pittsburgh and 11:43 PM in Chicago Loop.
Pittsburgh to Chicago Loop train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Pittsburgh to Chicago Loop is 464 miles. It takes approximately 7h 36m to drive from Pittsburgh to Chicago Loop.
Book your Pittsburgh to Chicago Loop train tickets online with Omio.
There are 1260+ hotels available in Chicago Loop.