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Pisa to Frosinone buses

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Trip Overview

The average bus between Pisa and Frosinone takes 12h 36m and the fastest bus takes 8h 50m. The bus runs, on average, 6 times per week from Pisa to Frosinone. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

12h 36m
Duration
458 km
Distance
€33
Average price
6 times a week
Frequency

Pisa to Frosinone bus times

Buses run 6 times a week between Pisa and Frosinone. The service departs Pisa at 10:00 PM at night, which arrives into Frosinone at 05:28:00. All services require a transfer at Florence Villa Constanza Bus Station and take an average of 12h 36m. The schedules shown below are for the next available departures.

Departing Saturday, November 7, 2026

  •  → 

    Arrives +2 days

    FlixBusItabus S.p.A.Cotral S.p.A.31h 28m • 2 changes

Departing Sunday, November 8, 2026

  •  → 

    Arrives next day

    FlixBusItabus S.p.A.Cotral S.p.A.8h 50m • 2 changes

Departing Monday, November 9, 2026

  •  → 

    Arrives next day

    FlixBusItabus S.p.A.Cotral S.p.A.8h 50m • 2 changes

Departing Tuesday, November 10, 2026

  •  → 

    Arrives next day

    FlixBusItabus S.p.A.Cotral S.p.A.8h 50m • 2 changes

Departing Wednesday, November 11, 2026

  •  → 

    Arrives next day

    FlixBusItabus S.p.A.Cotral S.p.A.8h 50m • 2 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    FlixBusItabus S.p.A.Cotral S.p.A.8h 50m • 2 changes

Frequently asked questions

Want to know about travelling from Pisa to Frosinone? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Pisa to Frosinone.ExpandLaunch map view
  • Distance: 457.6 km
  • Duration: 12h 36m

What companies run services between Pisa, Italy and Frosinone, Lazio, Italy?

You can take a bus from Pisa to FROSINONE | Via Moro Via Piave # f3475 via Florence Villa Constanza Bus Station, Florence - Villa Costanza, and FROSINONE | Piazza Pertini # f3486 in around 7h 22m.

Operators