The average bus between Philadelphia and Manlius takes 12h 10m and the fastest bus takes 8h 26m. The bus service runs several times per day from Philadelphia to Manlius. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Philadelphia and Manlius. The earliest departure is at 6:05 AM in the morning, and the last departure from Philadelphia is at 7:30 PM which arrives into Manlius at 7:11 AM. All services require a transfer at Newark Penn Station and take an average of 12h 10m. The schedules shown below are for the next available departures.



8h 26m • 3 changes
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17h 21m • 3 changes
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12h 26m • 3 changes



10h • 3 changes



8h 26m • 3 changes
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17h 21m • 3 changes
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12h 26m • 3 changes



10h • 3 changes



8h 26m • 3 changes
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17h 21m • 3 changes
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11h 41m • 3 changes
Want to know about travelling from Philadelphia to Manlius? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Philadelphia to Manlius. However, there are services departing from Philadelphia station and arriving at Manlius station via Newark Penn Station station. The journey, including transfers, takes approximately 12h 10m.
Philadelphia to Manlius bus services, operated by Greyhound USA, depart from Philadelphia Bus Station.
Philadelphia to Manlius bus services, operated by Greyhound USA, arrive at Syracuse Bus Station.
The distance between Philadelphia and Manlius is 345.8 km. The road distance is 540 km.
You can take a bus from Philadelphia Bus Station to Fayette St & W Seneca St via Newark Penn Station, Regional Transportation Center, B14, and A2 in around 9h 27m.