The average bus between Manhattan and Manlius takes 8h 32m and the fastest bus takes 6h 26m. The bus service runs several times per day from Manhattan to Manlius. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Manhattan and Manlius. The earliest departure is at 9:20 AM in the morning, and the last departure from Manhattan is at 11:59 PM which arrives into Manlius at 7:11 AM. All services require a transfer at Regional Transportation Center and take an average of 8h 32m. The schedules shown below are for the next available departures.
Arrives next day


14h 6m • 2 changes
Arrives next day


7h 12m • 2 changes


6h 45m • 2 changes


6h 46m • 2 changes


6h 26m • 2 changes
Arrives next day


14h 6m • 2 changes


6h 45m • 2 changes


6h 46m • 2 changes


6h 26m • 2 changes
Arrives next day


14h 6m • 2 changes


6h 45m • 2 changes


6h 46m • 2 changes


6h 26m • 2 changes
Arrives next day


14h 6m • 2 changes
Want to know about travelling from Manhattan to Manlius? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Manhattan to Manlius. However, there are services departing from Manhattan station and arriving at Manlius station via Syracuse Bus Station station. The journey, including transfers, takes approximately 8h 32m.
Manhattan to Manlius bus services, operated by Flixbus USA, depart from New York Midtown station.
Manhattan to Manlius bus services, operated by Flixbus USA, arrive at Syracuse Bus Station.
The distance between Manhattan and Manlius is 297.6 km. The road distance is 443 km.
Flixbus USA operates a bus from New York Midtown to Syracuse Bus Station every 3 hours. Tickets cost $30–60 and the journey takes 4h 40m.