The average bus between Otranto and Roma Termini takes 11h 12m and the fastest bus takes 10h 35m. The bus service runs several times per day from Otranto to Roma Termini. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Otranto and Roma Termini. The earliest departure is at 7:10 AM in the morning, and the last departure from Otranto is at 6:48 PM which arrives into Roma Termini at 5:35 AM. All services require a transfer at Lecce and take an average of 11h 12m. The schedules shown below are for the next available departures.


10h 44m • 2 changes


11h 47m • 2 changes
Arrives next day


11h 5m • 2 changes
Arrives next day


10h 57m • 2 changes


10h 44m • 2 changes


11h 47m • 2 changes
Arrives next day


10h 57m • 2 changes


10h 44m • 2 changes


11h 47m • 2 changes
Arrives next day


11h 5m • 2 changes
Arrives next day


10h 57m • 2 changes


10h 44m • 2 changes


11h 47m • 2 changes
Arrives next day


11h 55m • 2 changes
Arrives next day


10h 57m • 2 changes
Want to know about travelling from Otranto to Roma Termini? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Otranto to Roma Termini. However, there are services departing from Otranto station and arriving at Roma Termini station via Lecce - City Terminal. The journey, including transfers, takes approximately 11h 12m.
Otranto to Roma Termini bus services, operated by Salento in bus, depart from Otranto - Stazione FSE station.
Otranto to Roma Termini bus services, operated by Salento in bus, arrive at Roma, Autostazione Tiburtina station.
The distance between Otranto and Roma Termini is 538.4 km. The road distance is 668 km.
You can take a bus from Otranto - Stazione FSE to Termini via Lecce and Roma, Autostazione Tiburtina in around 11h 23m.