The average bus between Orlando and Seffner takes 4h 42m and the fastest bus takes 3h 16m. The bus service runs several times per day from Orlando to Seffner. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Orlando and Seffner. The earliest departure is at 4:25 AM at night, and the last departure from Orlando is at 8:45 PM which arrives into Seffner at 5:47 AM. All services require a transfer at Tampa Bus Station and take an average of 4h 42m. The schedules shown below are for the next available departures.


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Arrives next day


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3h 16m • 2 changes


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3h 52m • 2 changes


3h 16m • 2 changes


3h 31m • 2 changes


3h 58m • 2 changes


3h 52m • 2 changes


3h 22m • 2 changes


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3h 57m • 2 changes
Want to know about travelling from Orlando to Seffner? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Orlando to Seffner. However, there are services departing from Orlando station and arriving at Seffner station via Tampa Bus Station station. The journey, including transfers, takes approximately 4h 42m.
Orlando to Seffner bus services, operated by Flixbus USA, depart from Orlando Bus Station.
Orlando to Seffner bus services, operated by Flixbus USA, arrive at Tampa Bus Station.
The distance between Orlando and Seffner is 107.3 km. The road distance is 158 km.
Flixbus USA operates a bus from Orlando Bus Station to Tampa Bus Station every 4 hours. Tickets cost $11–19 and the journey takes 1h 35m. Greyhound USA also services this route once daily.