The average bus between Fort Myers and Seffner takes 6h 34m and the fastest bus takes 4h 16m. The bus service runs several times per day from Fort Myers to Seffner. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Fort Myers and Seffner. The earliest departure is at 10:55 AM in the morning, and the last departure from Fort Myers is at 6:55 PM which arrives into Seffner at 6:37 AM. All services require a transfer at Fort Myers 7-11 and take an average of 6h 34m. The schedules shown below are for the next available departures.


4h 54m • 2 changes


5h 3m • 2 changes


4h 16m • 2 changes
Arrives next day


10h 52m • 2 changes


4h 54m • 2 changes


5h 3m • 2 changes
Arrives next day


10h 52m • 2 changes


4h 54m • 2 changes


5h 3m • 2 changes


4h 16m • 2 changes
Arrives next day


10h 52m • 2 changes


4h 54m • 2 changes


5h 3m • 2 changes


4h 16m • 2 changes
Arrives next day


11h 42m • 2 changes
Want to know about travelling from Fort Myers to Seffner? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Fort Myers to Seffner. However, there are services departing from Fort Myers station and arriving at Seffner station via University of South Florida Tampa. The journey, including transfers, takes approximately 6h 34m.
Fort Myers to Seffner bus services, operated by Flixbus USA, depart from Fort Myers 7-11 station.
Fort Myers to Seffner bus services, operated by Flixbus USA, arrive at University of South Florida Tampa station.
Book your Fort Myers to Seffner bus tickets online with Flixbus USA and Hillsborough Area Regional Transit.
The distance between Fort Myers and Seffner is 157.4 km. The road distance is 243 km.
RedCoach operates a bus from Fort Myers 7-11 to University of South Florida Tampa twice daily. Tickets cost $30–60 and the journey takes 2h 15m.