The average bus between Fort Myers and Seffner takes 6h 40m and the fastest bus takes 4h 28m. The bus service runs several times per day from Fort Myers to Seffner. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Fort Myers and Seffner. The earliest departure is at 10:45 AM in the morning, and the last departure from Fort Myers is at 6:40 PM which arrives into Seffner at 6:37 AM. All services require a transfer at Tampa Bus Station and take an average of 6h 40m. The schedules shown below are for the next available departures.


5h 36m • 2 changes


4h 29m • 2 changes
Arrives next day


11h 7m • 2 changes


5h 2m • 2 changes


5h 36m • 2 changes


4h 29m • 2 changes
Arrives next day


11h 7m • 2 changes


5h 2m • 2 changes


5h 36m • 2 changes


4h 29m • 2 changes
Arrives next day


11h 7m • 2 changes


5h 2m • 2 changes


5h 36m • 2 changes


4h 29m • 2 changes
Arrives next day


11h 57m • 2 changes
Want to know about travelling from Fort Myers to Seffner? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Fort Myers to Seffner. However, there are services departing from Fort Myers station and arriving at Seffner station via Tampa Bus Station station. The journey, including transfers, takes approximately 6h 40m.
Fort Myers to Seffner bus services, operated by Flixbus USA, depart from Fort Myers Bus Stop station.
Fort Myers to Seffner bus services, operated by Flixbus USA, arrive at Tampa Bus Station.
The distance between Fort Myers and Seffner is 157.4 km. The road distance is 225 km.
Flixbus USA operates a bus from Fort Myers Bus Stop to Tampa Bus Station 4 times a day. Tickets cost $16–28 and the journey takes 2h 50m.