The average bus between Berwyn and St. Louis takes 7h 48m and the fastest bus takes 6h 54m. The bus service runs several times per day from Berwyn to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Berwyn and St. Louis. The earliest departure is at 8:46 AM in the morning, and the last departure from Berwyn is at 9:00 PM which arrives into St. Louis at 6:25 AM. All services require a transfer at Jefferson & Harrison and take an average of 7h 48m. The schedules shown below are for the next available departures.

6h 54m • 1 change

7h 5m • 1 change
Arrives next day

9h 25m • 1 change

6h 54m • 1 change

7h 5m • 1 change
Arrives next day

9h 25m • 1 change
Want to know about travelling from Berwyn to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Berwyn to St. Louis. However, there are services departing from Berwyn station and arriving at St. Louis station via St Louis Bus Station station. The journey, including transfers, takes approximately 7h 48m.
Berwyn to St. Louis bus services, operated by Chicago Transit (CTA), depart from Chicago Bus Station.
Berwyn to St. Louis bus services, operated by Chicago Transit (CTA), arrive at St Louis Bus Station.
The distance between Berwyn and St. Louis is 412.4 km. The road distance is 525 km.
Flixbus USA operates a bus from Chicago Bus Station to St Louis Bus Station 3 times a day. Tickets cost $40–75 and the journey takes 5h 55m.