Naples to Sistine Chapel bus times
Buses run hourly between Naples and Sistine Chapel. The earliest departure is at 2:40 AM at night, and the last departure from Naples is at 10:35 PM which arrives into Sistine Chapel at 5:57 AM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 3h 41m. The schedules shown below are for the next available departures.
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3h 34m • 1 change
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3h 30m • 1 change
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3h 29m • 1 change
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3h 38m • 1 change
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Departing Sunday, August 16, 2026
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3h 21m • 1 change
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3h 23m • 1 change
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3h 17m • 1 change
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3h 19m • 1 change
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Departing Monday, August 17, 2026
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3h 21m • 1 change
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3h 23m • 1 change
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3h 17m • 1 change
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3h 19m • 1 change
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