The average bus between Mulhouse and Lyon takes 5h 21m and the fastest bus takes 4h 25m. The bus service runs several times per day from Mulhouse to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Mulhouse and Lyon. The earliest departure is at 3:05 AM at night, and the last departure from Mulhouse is at 10:10 PM which arrives into Lyon at 2:35 AM. All services run direct with no transfers required, and take on average 5h 21m. The schedules shown below are for the next available departures.
Arrives next day
Arrives next day
Arrives next day
Want to know about travelling from Mulhouse to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Mulhouse station and arriving at Lyon station. Services depart 5 times a day, and operate Twice daily. The journey takes approximately 5h 21m.
Mulhouse to Lyon bus services, operated by FlixBus, depart from Mulhouse station.
Mulhouse to Lyon bus services, operated by FlixBus, arrive at Lyon station.
Book your Mulhouse to Lyon bus tickets online with FlixBus.
The distance between Mulhouse and Lyon is 292.2 km. The road distance is 379 km.
FlixBus operates a bus from Mulhouse to Lyon every 4 hours. Tickets cost €26–45 and the journey takes 4h 35m. BlaBlaCar Bus also services this route twice daily.