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Mississauga to Pittsburgh buses

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Trip Overview

The bus between Mississauga and Pittsburgh takes 34h 24m. The bus runs, on average, 4 times per week from Mississauga to Pittsburgh. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

34h 24m
Duration
345 mi
Distance
$70
Average price
4 times a week
Frequency

Mississauga to Pittsburgh bus times

Buses run 4 times a week between Mississauga and Pittsburgh. The service departs Mississauga at 5:46 AM in the morning, which arrives into Pittsburgh at 16:10:00. All services require a transfer at Union Station Bus Terminal and take an average of 34h 24m. The schedules shown below are for the next available departures.

Departing Tuesday, November 3, 2026

  •  → 

    Arrives next day

    GO TransitFlixbus USAGreyhound USA34h 24m • 2 changes

Departing Thursday, November 5, 2026

  •  → 

    Arrives next day

    GO TransitFlixbus USAGreyhound USA34h 24m • 2 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives next day

    GO TransitFlixbus USAGreyhound USA34h 24m • 2 changes

Frequently asked questions

Want to know about travelling from Mississauga to Pittsburgh? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Mississauga to Pittsburgh.ExpandLaunch map view
  • Distance: 344.7 mi
  • Duration: 34h 24m

What companies run services between Mississauga, ON, Canada and Pittsburgh, PA, USA?

You can take a bus from Rathburn Rd. W. @ Mavis Rd. to Pittsburgh Intermodal Station via Union Station Bus Terminal, Toronto, and Erie in around 11h 9m.

Operators